1988
DOI: 10.1093/clinchem/34.2.422
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Colorimetry of p-aminohippurate in the presence of sulfamethoxazole.

Abstract: Colorimetric quantification of p-aminohippurate (PAH), which is helpful in assessment of renal function, is subject to interference from sulfa compounds such as sulfamethoxazole. We were unable to measure serum PAH in two patients receiving a trimethoprim-sulfamethoxazole combination because of interference by the latter with the colorimetric estimation. We found that isoamyl acetate removes sulfamethoxazole from the samples without influencing PAH. The extraction is simple, inexpensive, and reproducible.

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Cited by 3 publications
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“…Free primary o-and m-aminoaromatic compounds (19), phenols, tryptophan, and indican also give color reactions (23). Interference from some sulfa drugs, such as sulfamethoxazole, can be overcome with isoamyl acetate extraction (17), and this assay has even been automated (11,13). Nevertheless, fresh preparation of reagents (nitrite, sulfamate), sequential addition of three reagents, the timing of which is critical, and temperature dependence of these assays make these techniques cumbersome.…”
Section: Discussionmentioning
confidence: 99%
“…Free primary o-and m-aminoaromatic compounds (19), phenols, tryptophan, and indican also give color reactions (23). Interference from some sulfa drugs, such as sulfamethoxazole, can be overcome with isoamyl acetate extraction (17), and this assay has even been automated (11,13). Nevertheless, fresh preparation of reagents (nitrite, sulfamate), sequential addition of three reagents, the timing of which is critical, and temperature dependence of these assays make these techniques cumbersome.…”
Section: Discussionmentioning
confidence: 99%
“…Dans l'Art, c'est la création qui joue le rôle initial fondateur, non la contemplation ; dans le domaine scientifique, c'est la recherche et non le trésor des vérités acquises »49 .Or, l'action imprègne l'approche ethnographique de Preuss, que ce soit par la place prépondérante qu'il accorde à l'observation des rituels ou au registre de la parole mythique à travers les chants cérémoniels. Preuss s'est intéressé de beaucoup plus près que ses prédécesseurs aux contextes rituels dans lesquels ces artefacts étaient élaborés50 . Issu de l'école diffusionniste allemande du début du siècle, dépositaire d'une solide connaissance de la littérature ethnologique et des approches philologiques de l'époque, son travail titanesque de registre des chants et mythes en langue vernaculaire et leur traduction en allemand l'a conduit à confronter constamment ces textes avec ses observations dans les cérémonies et fêtes des Huichol, Cora et Mexicanero.…”
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