2023
DOI: 10.1016/j.aca.2023.341322
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Combination of specific proteins as markers for accurate detection of extracellular vesicles using proximity ligation-mediated bHCR amplification

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Cited by 4 publications
(1 citation statement)
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“…Zhu et al described a cascade bHCR amplification activated by co-marker recognition, which generates multiple G-quadruplex structures combined with fluorescent dyes to facilitate signal transduction. This method significantly improves accurate detection by effectively minimizing false positives caused by interfering proteins or individual protein markers 113 . Additionally, various advanced approaches have been reported, such as employing DNA nanostructures as "nanoweights" to enrich cancerous EVs 114 , and utilizing CRISPR-Cas12a assisted HCR 115 .…”
Section: Detection Of Evsmentioning
confidence: 99%
“…Zhu et al described a cascade bHCR amplification activated by co-marker recognition, which generates multiple G-quadruplex structures combined with fluorescent dyes to facilitate signal transduction. This method significantly improves accurate detection by effectively minimizing false positives caused by interfering proteins or individual protein markers 113 . Additionally, various advanced approaches have been reported, such as employing DNA nanostructures as "nanoweights" to enrich cancerous EVs 114 , and utilizing CRISPR-Cas12a assisted HCR 115 .…”
Section: Detection Of Evsmentioning
confidence: 99%