Combined adenoid cystic and squamous carcinoma of Bartholin's gland. Case report

Webb, John; Lott, Marie-Catherine; O'Sullivan, Janet; Azzopardi, J. G.

doi:10.1111/j.1471-0528.1984.tb04772.x

Cited by 8 publications

(1 citation statement)

References 5 publications

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“…According to our assessment of the English literature, the dedifferentiation of vulvar ACC, particularly ACC of Bartholin's gland with a high-grade SCC component, has not been specifically documented. In 1984, Webb et al described a case of a 58-year-old woman who suffered from combined ACC and squamous carcinoma of the Bartholin's gland [6]. They discussed how the excretory ducts of the Bartholin's gland are thought to be the source of the SCC component (i.e., collision cancer).…”

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confidence: 99%

Vulvar Adenoid Cystic Carcinoma with Squamous Cell Carcinoma Component

HAN,

KATO,

MORINAGA

et al. 2022

Kurume Med. J.

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We report a rare case of vulvar adenoid cystic carcinoma (ACC) with a squamous cell carcinoma (SCC) component. A 78-year-old woman presented with a nodule in the left side of her vulva for 30 years. In the past few years, the nodule had increased in size and was accompanied by pain and discomfort during squatting. Physical examination revealed a firm vulvar chicken egg-sized mass with poor mobility. The findings of routine blood tests, including major tumor markers, were within normal ranges. No abnormalities were observed in the internal genitals or intestinal tracts. Magnetic resonance imaging revealed a tumor located under the skin of the perineum with a cystic change in fibrous partitions. It showed high intensity on T1-weighted images and high intensity with nonuniformity on T2-weighted images. No metastatic le-

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mentioning

confidence: 99%

Vulvar Adenoid Cystic Carcinoma with Squamous Cell Carcinoma Component

HAN,

KATO,

MORINAGA

et al. 2022

Kurume Med. J.

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Adenoid cystic carcinoma of bartholin's gland: Review of the literature and report of two cases

Abräo

Marques

Marziona

et al. 1985

Journal of Surgical Oncology

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Two patients with adenoid cystic carcinoma of Bartholin's gland and a review of the relevant literature are presented. With the inclusion of these two patients, there are now 24 cases reported. Both patients had large vulvar masses with a short clinical history, and several local tumor recurrences within the first 21/2 years after radical vulvectomy. The characteristic cribriform pattern and perineural involvement in addition to vascular invasion were present in the pathological material. No metastases were found in the inguino-femoral lymph nodes removed. Both patients are alive, without evidence of local recurrence but with lung metastases. A chemotherapeutic treatment scheme (adriamycin and cyclophosphamide) is underway but it is too early to evaluate its results.

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