Combined application of multinozzle air-jet electrospinning and airflow twisting for the efficient preparation of continuous twisted nanofiber yarn

He, Jianxin; Qi, Kun; Wang, Lidan; Zhou, Yuman; Liu, Rangtong; Cui, Shizhong

doi:10.1007/s12221-015-1319-8

Cited by 22 publications

(17 citation statements)

References 22 publications

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“…Furthermore, the twists in the yarns generated by the rotation of the funnel do improve the mechanical properties, allowing it to meet the requirements for textile processing. 28 , 29 …”

Section: Introductionmentioning

confidence: 99%

Fabrication of Multilayered Nanofiber Scaffolds with a Highly Aligned Nanofiber Yarn for Anisotropic Tissue Regeneration

Tao

Shen

et al. 2020

ACS Omega

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Nanofibrous scaffolds were widely studied to construct scaffold for various fields of tissue engineering due to their ability to mimic a native extracellular matrix (ECM). However, generally, an electrospun nanofiber exhibited a two-dimensional (2D) membrane form with a densely packed structure, which inhibited the formation of a bulk tissue in a three-dimensional (3D) structure. The appearance of a nanofiber yarn (NFY) made it possible to further process the electrospun nanofiber into the desired fabric for specific tissue regeneration. Here, poly( l -lactic acid) (PLLA) NFYs composed of a highly aligned nanofiber were prepared via a dual-nozzle electrospinning setup. Afterward, a noobing technique was applied to fabricate multilayered scaffolds with three orthogonal sets of PLLA NFYs, without interlacing them. Thus the constituent NFYs of the fabric were free of any crimp, apart from the binding yarn, which was used to maintain the integrity of the noobing scaffold. Remarkably, the highly aligned PLLA NFY expressed strengthened mechanical properties than that of a random film, which also promoted the cell adhesion on the NFY scaffold with unidirectional topography and less spreading bodies. In vitro experiments indicated that cells cultured on a noobing NFY scaffold showed a higher proliferation rate during long culture period. The controllable pore structure formed by the vertically arrayed NFY could allow the cell to penetrate through the thickness of the 3D scaffold, distributed uniformly in each layer. The topographic clues guided the orientation of H9C2 cells, forming tissues on different layers in two perpendicular directions. With NFY as the building blocks, noobing and/or 3D weaving methods could be applied in the fabrication of more complex 3D scaffolds applied in anisotropic tissues or organs regeneration.

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“…Furthermore, the twists in the yarns generated by the rotation of the funnel do improve the mechanical properties, allowing it to meet the requirements for textile processing. 28 , 29 …”

Section: Introductionmentioning

confidence: 99%

Fabrication of Multilayered Nanofiber Scaffolds with a Highly Aligned Nanofiber Yarn for Anisotropic Tissue Regeneration

Tao

Shen

et al. 2020

ACS Omega

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“…Traditionally, electrospinning has been performed using a syringe that presses a molten or dissolved polymer through a needle; a high electric field then drags the polymer solution to a substrate on which it is placed. Needleless technologies, however, are of high interest as they allow processes to be upscaled to an industrial scale [3] and sometimes enable introducing special properties of the resulting nanofiber mats, such as a high orientation of the fibers [4,5].…”

Section: Introductionmentioning

confidence: 99%

New Polymers for Needleless Electrospinning from Low-Toxic Solvents

et al. 2019

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Electrospinning is a new technology whose scope is gradually being developed. For this reason, the number of known polymer–solvent combinations for electrospinning is still very low despite the enormous variety of substances that are potentially available. In particular, electrospinning from low-toxic solvents, such as the use of dimethyl sulfoxide (DMSO) in medical technology, is rare in the relevant scientific literature. Therefore, we present in this work a series of new polymers that are applicable for electrospinning from DMSO. From a wide range of synthetic polymers tested, poly(vinyl alcohol) (PVOH), poly(2ethyl2oxazolene) (PEOZ), and poly(vinylpyrrolidone) (PVP) as water-soluble polymers and poly(styrene-co-acrylonitrile) (SAN), poly(vinyl alcohol-co-ethylene) (EVOH), and acrylonitrile butadiene styrene (ABS) as water-insoluble polymers were found to be suitable for the production of nanofibers. Furthermore, the influence of acetone as a volatile solvent additive in DMSO on the fiber morphology of these polymers was investigated. Analyses of the fiber morphology by helium ion microscopy (HIM) showed significantly different fiber diameters for different polymers and a reduction in beads and branches with increasing acetone content.

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“…The applications of electrospun nanofibers as commercial products need to resolve two important issues, i.e., production on a large scale and at a relatively low cost [ 66 , 67 ]. In the literature, many new methods have been reported about the creation of nanofibers on a large scale such as multiple-needle electrospinning [ 68 ], needleless electrospinning [ 69 ], multinozzle air-jet electrospinning [ 70 ], and so on. The strategy reported here for cutting the cost of electrospun nanofibers due to electrical consumption can be combined with those large-scale production methods for a bright future of commercial electrospun products.…”

Section: Resultsmentioning

confidence: 99%

Energy-Saving Electrospinning with a Concentric Teflon-Core Rod Spinneret to Create Medicated Nanofibers

et al. 2020

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Although electrospun nanofibers are expanding their potential commercial applications in various fields, the issue of energy savings, which are important for cost reduction and technological feasibility, has received little attention to date. In this study, a concentric spinneret with a solid Teflon-core rod was developed to implement an energy-saving electrospinning process. Ketoprofen and polyvinylpyrrolidone (PVP) were used as a model of a poorly water-soluble drug and a filament-forming matrix, respectively, to obtain nanofibrous films via traditional tube-based electrospinning and the proposed solid rod-based electrospinning method. The functional performances of the films were compared through in vitro drug dissolution experiments and ex vivo sublingual drug permeation tests. Results demonstrated that both types of nanofibrous films do not significantly differ in terms of medical applications. However, the new process required only 53.9% of the energy consumed by the traditional method. This achievement was realized by the introduction of several engineering improvements based on applied surface modifications, such as a less energy dispersive air-epoxy resin surface of the spinneret, a free liquid guiding without backward capillary force of the Teflon-core rod, and a smaller fluid–Teflon adhesive force. Other non-conductive materials could be explored to develop new spinnerets offering good engineering control and energy savings to obtain low-cost electrospun polymeric nanofibers.

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Combined application of multinozzle air-jet electrospinning and airflow twisting for the efficient preparation of continuous twisted nanofiber yarn

Cited by 22 publications

References 22 publications

Fabrication of Multilayered Nanofiber Scaffolds with a Highly Aligned Nanofiber Yarn for Anisotropic Tissue Regeneration

Fabrication of Multilayered Nanofiber Scaffolds with a Highly Aligned Nanofiber Yarn for Anisotropic Tissue Regeneration

New Polymers for Needleless Electrospinning from Low-Toxic Solvents

Energy-Saving Electrospinning with a Concentric Teflon-Core Rod Spinneret to Create Medicated Nanofibers

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