2013
DOI: 10.1007/s00330-013-2771-8
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Combined contrast-enhanced magnetic resonance and diffusion-weighted imaging reading adapted to the “Breast Imaging Reporting and Data System” for multiparametric 3-T imaging of breast lesions

Abstract: Multiparametric 3-T MRI of the breast using a BI-RADS-adapted reading is fast, simple to use and significantly improves the diagnostic accuracy of breast MRI. KEYPOINTS : • Multiparametric breast 3-T MRI with BI-RADS-adapted reading improves diagnostic accuracy. • BI-RADS-adapted reading of CE-MRI and DWI is based on established reporting guidelines. • BI-RADS-adapted reading is fast and easy to use in routine clinical practice. • BI-RADS-adapted reading is robust to intra- and inter-reader variability.

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Cited by 112 publications
(102 citation statements)
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“…For the assessment of the enhancement kinetics of masses, an automated semiquantitative curve type analysis was performed using a dedicated software (Syngo BreVis, Siemens). For NME, the enhancement kinetics were not considered (8,19,21,22). The probability of malignancy was determined by assigning a final BI-RADS category as summarized in Supplementary Table S2 (8).…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…For the assessment of the enhancement kinetics of masses, an automated semiquantitative curve type analysis was performed using a dedicated software (Syngo BreVis, Siemens). For NME, the enhancement kinetics were not considered (8,19,21,22). The probability of malignancy was determined by assigning a final BI-RADS category as summarized in Supplementary Table S2 (8).…”
Section: Discussionmentioning
confidence: 99%
“…In this study, these parameters had higher specificities, but, for this increase in specificity, there was a trade-off in sensitivity. In addition, neither DWI nor 3D 1 H-MRSI are standalone parameters and cannot be used for diagnosis without the information provided by DCE-MRI (18,22). 18 FDG-PET has a sensitivity comparable to DWI and 3D 1 H-MRSI and, similar to DCE-MRI, is limited in specificity (3).…”
Section: Discussionmentioning
confidence: 99%
“…In comparison with all other breast magnetic resonance imaging (MRI) techniques, dynamic contrast-enhanced MRI (DCE-MRI) and apparent diffusion coefficient (ADC) calculated using diffusion-weighted MRI (DW-MRI) are the most widely used [1,2]. However, the overlaps of DCE-MRI and ADC in malignant and benign breast lesions indicate that neither is as such the best tool for diagnosing breast lesions [3,4,5,6].…”
Section: Introductionmentioning
confidence: 99%
“…Die kombinierte Anwendung dieser Parameter wird als multiparametrische Bildgebung definiert [4][5][6][7][8]. Diese ermöglicht sowohl die Erfassung der Tumormorphologie als auch die Quantifizierung und Visualisierung biologischer, physiologischer und pathologischer Prozesse auf zellulärer und molekularer Ebene, die bei der Krebsentstehung und -progression beteiligt sind.…”
Section: Hintergrundunclassified
“…MR-Parameter verwendet, und es besteht bisher kein Konsensus, wie die jeweilige einzigartige Information der KM-MRT und der DWI zu kombinieren ist. Um das Dilemma zu lösen, entwickelten Pinker et al [48] ein Auswertungsschema, welches die ADC-Schwellenwerte an die vergebene BI-RADS-Klassifikation (Breast Imaging Reporting and Data System) adaptiert und verglichen dieses mit den bisher publizierten Kombinationsvorschlägen. Durch diese BI-RADSadaptierte kombinierte Auswertung der KM-MRT und DWI konnte die ausgezeichnete Sensitivität der KM-MRT bei gleichzeitiger signifikanter Steigerung der Spezifität erhalten werden (p = 0,001).…”
Section: Chemical-exchange-saturationtransfer(cest)-bildgebungunclassified