Combined effect of the head groups and alkyl chains of archaea lipids when interacting with bacteriorhodopsin

Umegawa, Yuichi; Kawatake, Satoshi; Murata, Michio; Matsuoka, Shigeru

doi:10.1016/j.bpc.2023.106959

Cited by 3 publications

(1 citation statement)

References 60 publications

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“…GGRs are flavoenzymes found in archaea, plants, and photosynthetic bacteria (Wang et al 2014 ; Tsukatani et al 2022 ; Nishimura and Eguchi 2006 ). They are promiscuous and can catalyze the partial or complete saturation of a variety of substrates, including DGGGP, GGPP, FPP, farnesol (FOH), and geranylgeraniol (GOH) (Sasaki et al 2011 ; Meadows et al 2018 ).…”

Section: Saturation In Archaeal Membranesmentioning

confidence: 99%

Unraveling the multiplicity of geranylgeranyl reductases in Archaea: potential roles in saturation of terpenoids

Rao,

Driessen

2024

Extremophiles

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The enzymology of the key steps in the archaeal phospholipid biosynthetic pathway has been elucidated in recent years. In contrast, the complete biosynthetic pathways for proposed membrane regulators consisting of polyterpenes, such as carotenoids, respiratory quinones, and polyprenols remain unknown. Notably, the multiplicity of geranylgeranyl reductases (GGRs) in archaeal genomes has been correlated with the saturation of polyterpenes. Although GGRs, which are responsible for saturation of the isoprene chains of phospholipids, have been identified and studied in detail, there is little information regarding the structure and function of the paralogs. Here, we discuss the diversity of archaeal membrane-associated polyterpenes which is correlated with the genomic loci, structural and sequence-based analyses of GGR paralogs.

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Section: Saturation In Archaeal Membranesmentioning

confidence: 99%

Unraveling the multiplicity of geranylgeranyl reductases in Archaea: potential roles in saturation of terpenoids

Rao,

Driessen

2024

Extremophiles

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Boolean Logic Gate Operation in Bacteriorhodopsin of Purple Membrane Based on a Molten Globule‐like State

Mostafa

2024

ChemPhysChem

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Bacteriorhodopsin (bR) of purple membrane (PM) has increasing technical interests, particularly in photonic devices and bioelectronics. The present work has concerned with monitoring the temperature dependence of passive electric responses in‐plane and out‐of‐plane of the membranes. Based on thermal properties observed orthogonally here for PM, a high‐temperature intermediate of bR has been suggested to populate at around 60 °C, which may be ascribed to a molten globule‐like state. This intermediate has been found to be enclosed between two reversible thermal transitions for PM. Large‐scale turnover in the energy of activation, for these two thermal transitions, occurs steeply at such state at 60 °C, above which does bR reverse the sign of dielectric anisotropy (i.e. crossover) provided the operating frequency should be above the crossover frequency, at which the reversal occurs. No such crossover was found to occur below the crossover frequency, even above the crossover temperature (i.e. 60 °C). Likewise, no such crossover was found to occur below the crossover temperature, even above the crossover frequency. Relying on this reasoning, a logic gate operation may be declared implicating bR for bioelectronics and sense technological relevance. In addition, the results specify “dual frequency” as well as “dual temperature” characteristics to bacteriorhodopsin.

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Detection of bacteriorhodopsin trimeric rotation at thermal phase transitions of purple membrane in suspension

Mostafa

2023

Biophysical Chemistry

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Combined effect of the head groups and alkyl chains of archaea lipids when interacting with bacteriorhodopsin

Cited by 3 publications

References 60 publications

Unraveling the multiplicity of geranylgeranyl reductases in Archaea: potential roles in saturation of terpenoids

Unraveling the multiplicity of geranylgeranyl reductases in Archaea: potential roles in saturation of terpenoids

Boolean Logic Gate Operation in Bacteriorhodopsin of Purple Membrane Based on a Molten Globule‐like State

Detection of bacteriorhodopsin trimeric rotation at thermal phase transitions of purple membrane in suspension

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