1997
DOI: 10.1016/s0892-0362(97)00049-4
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Combined effects of a simultaneous exposure to noise and toluene on hearing function

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Cited by 81 publications
(69 citation statements)
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“…: Experiments with rats have shown that combined exposure to noise and solvents (such as toluene, styrene, and ethylbenzene) induces synergistic adverse effects on hearing. [77][78][79][80][81] In most of these investigations, high concentrations of solvents were used for short intervals of time, conditions which do not accurately reflect occupational exposure conditions.…”
Section: Co-exposurementioning
confidence: 99%
“…: Experiments with rats have shown that combined exposure to noise and solvents (such as toluene, styrene, and ethylbenzene) induces synergistic adverse effects on hearing. [77][78][79][80][81] In most of these investigations, high concentrations of solvents were used for short intervals of time, conditions which do not accurately reflect occupational exposure conditions.…”
Section: Co-exposurementioning
confidence: 99%
“…Os resultados mostraram a indução de perda auditiva, células ciliadas externas prejudicadas e estereocília danificada, com maior predominância nos ratos expostos simultaneamente ao ruído e ao tolueno. O dano coclear induzido pelo tolueno ou por ruído foi causado por dois mecanismos diferentes, envenenamento e mecânico (23).…”
Section: Discussionunclassified
“…In most factories where solvents or other chemicals are present, there is noise, too. An important fact that should be taken into consideration is that noise in conjunction with solvents may have a synergistic effect on hearing thresholds [14,15,16,17,18,19]. The group of solvent-exposed workers investigated in the present research was not exposed to noise levels above 85 dBA.…”
Section: Discussionmentioning
confidence: 99%