Combined endoscopic endonasal and posterior cervical approach to a clival chordoma

Chau, Anthony; Lazzaro, A.; Mobbs, Ralph J.; Teo, Charles

doi:10.1016/j.jocn.2010.04.007

Cited by 10 publications

(3 citation statements)

References 8 publications

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“…When considering the radical resection of the tumor, staged surgery plus adjuvant radiation (γ-knife) was recommended for the 15-year-old female patient, and the outcome was good at the time of follow-up. The results of the present case were similar to a case reported by Chau et al (17), in which a combined endoscopic endonasal and posterior cervical approach was used, together with proton radiotherapy, in an 18-year-old male with a clivus chordoma (17).…”

Section: Discussionsupporting

confidence: 90%

Familial chordoma: A case report and review of the literature

Wang

Tian

et al. 2015

Oncology Letters

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Abstract. Familial skull base chordoma is a rare tumor derived from the remnants of the embryonic notochord. The present study describes the clinical presentation of 4 cases of skull base chordomas in a family. A 15-year-old female received staged surgeries and was pathologically confirmed with a diagnosis of skull base chordoma. Among the patient's family, 2 members had previously undergone surgery and were pathologically confirmed with chordomas; 1 family member had also received radiation therapy. Furthermore, the patient's cousin, an 18-year-old male, was confirmed to have this condition by epipharyngoscopy. All confirmed cases within the family remained alive with the condition. A literature review of familial chordoma was undertaken and 8 chordoma pedigrees were found. Familial chordoma was rare, with an estimated rate of 0.4% in all chordomas. The skull base was the predominant location for familial chordoma. Compared with sporadic chordoma, familial chordomas were diagnosed at a younger age. The brachyury gene was strongly associated with familial chordomas, however, the exact pathogenesis and genetics mechanisms remains unclear.

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Section: Discussionsupporting

confidence: 90%

Familial chordoma: A case report and review of the literature

Wang

Tian

et al. 2015

Oncology Letters

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“…9 Also, the extension of the tumor downward as far as the upper cervical levels may require the application of rigid instrumentation as Chau et al describe in their case of a combined endoscopic endonasal and posterior cervical approach to a clival chordoma in a staged procedure. 10 However, in their case the total operative time for both procedures is described as 29 hours. This, as well as the necessity of repositioning the patient into a prone position, renders the combined use of a transnasal endoscopic and an open posterior approach impractical.…”

Section: Discussionmentioning

confidence: 99%

Combined Transnasal and Transcranial Removal of a Giant Clival Chordoma

et al. 2014

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Clival chordomas confront the surgeon with the task of resecting an aggressively invasive and destructive tumor in a critical surrounding. For many, mainly smaller, chordomas, the transnasal transclival approach is a feasible and safe surgical access. Larger tumors and especially those with extensive intradural, retrochiasmal, and/or deep cervical expansion are mostly approached by open craniotomy. Staged procedures are also commonly used in the case of expansive tumor growth. We present the first case of a single-session combined transnasal and transcranial approach to radically resect a large clival chordoma.

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“…A combination of operations with various surgical approaches are performed. [8][9][10][11][12] We report a very useful approach for lower clival chordoma that extends inferiorly to the spinal canal at the C2 level.…”

Section: Introductionmentioning

confidence: 99%

The C2 ganglion sectioning epidural approach to craniocervical junction chordoma: A technical case report

et al. 2012

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In chordoma, complete surgical removal of the epidural tumor should be the first choice of treatment. Numerous surgical approaches to clival chordoma have been described: anterior approaches, lateral approaches, and posterolateral approaches. A multistaged operation with a combination of these approaches is generally performed. We used three approaches to remove a clival chordoma extending from the lower clivus anteriorly to the anterior perivertebral space and inferiorly to the C2 level. The epidural posterolateral approach through the vertebral artery (VA)-C2 interval space after resection of the C2 dorsal ganglion was the most effective. To our knowledge, the epidural posterolateral approach below VA, referred to as C2 ganglion sectioning epidural approach has not been reported as an independent approach in detail. We report a two-year-old girl with a lower clival chordoma which has been excised using C2 ganglion sectioning epidural approach.

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Combined endoscopic endonasal and posterior cervical approach to a clival chordoma

Cited by 10 publications

References 8 publications

Familial chordoma: A case report and review of the literature

Familial chordoma: A case report and review of the literature

Combined Transnasal and Transcranial Removal of a Giant Clival Chordoma

The C2 ganglion sectioning epidural approach to craniocervical junction chordoma: A technical case report

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