PurposeThe research identifies literature on Home-Based Businesses (HBBs) from 2000 to August 2023, focuses on their economic roles, challenges for entrepreneurs and success strategies, reflecting societal and technological changes. This guides future studies and highlights knowledge gaps.Design/methodology/approachA systematic literature review of published, peer-reviewed research between the years 2000 and 2023 is performed to examine how research on HBBs has changed over time, areas needing more study and how research has been done.FindingsA total of 58 articles were analyzed and categorized into five distinct themes. Key insights into the evolution, significance and multifaceted aspects of HBBs are presented, revealing the impact and role of these businesses in a modern economic context.Originality/valueThe synthesis of existing literature enhances our understanding of recent studies on HBBs, focusing on challenges, and identifies promising directions for future research.