Community-Acquired Purulent Meningitis: A Review of 1,316 Cases During the Antibiotic Era, 1954-1976

Nosocomial meningitis caused by Klebsiella pneumoniae producing carbapenemase, with initial cerebrospinal fluid minimal inflammatory response

“…The occurrence of bacterial meningitis without or with minimal cellular response early in the course of the infection is rare 6 . Poor meningeal inflammatory response is usually observed in older patients or neonates, alcoholism, AIDSrelated immunosuppression, neoplastic, diabetes mellitus, or corticosteroid therapy.…”

“…Poor meningeal inflammatory response is usually observed in older patients or neonates, alcoholism, AIDSrelated immunosuppression, neoplastic, diabetes mellitus, or corticosteroid therapy. It is usually associated with low white blood cell count 6 . In the current case study, minimal CSF cell increase was observed, predominately in the form of lymphocytes.…”

Simultaneous Detection of Bacterial Meningitis in Suspected Cases of Meningitis in Children Using PCR Assay, In Taif, Saudi Arabia

“…The clinical signs and symptoms of BM vary according to several factors: age, duration of evolu tion of symptoms at the time of clinical examination, presence of underlying diseases and microorganism involved [11]. These signs have only 40-50% sensitivity in BM diagnosis [12].…”

Bacterial meningitis: An update review

“…Age (Geiseler et al, 1980): (extremes of age: elderly (age > 60 years); young children (age < 5 years), especially infants (age < 2years/newborns). 2.…”

“…4. Immuno-compromizing factors (Geiseler et al, 1980;Schutze et al, 2002): Post splenectomy, hematologic disorders such as sickle cell disease or thalassemia major, malignancy, diabetes, alcoholism/cirrhosis or HIV. 5.…”