Community‐based epidemiology of hepatitis B virus infection in West Bengal, India: Prevalence of hepatitis B e antigen‐negative infection and associated viral variants

Chowdhury, Abhijit; Santra, Amal; Chakravorty, Runu; Banerji, Arup; Pal, Sujay; Dhali, Gopal Krishna; Datta, Sibnarayan; Banerji, Soma; Manna, Byomkesh; Chowdhury, Sourav; Bhattacharya, Sujit; Mazumder, Debendranath Guha

doi:10.1111/j.1440-1746.2005.04070.x

Cited by 64 publications

(48 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…7 Studies have attributed 20-80% of all new hepatitis B infections to unsafe injections, and have also implicated unsafe injections as a major mode of transmission of hepatitis C. 8 Other studies have highlighted the various risk factors for HBV infection like being older than 20 years of age, poverty, a low level of education, use of reusable glass syringes, being shaved by a community barber, and being born at home. 9 A study conducted on Armed Forces population has found highly significant association of HBV positivity with having indulged in sex with CSWs and taking injections in civil set up. 4 …”

Section: Methodsmentioning

confidence: 99%

A study of seroprevalence of hepatitis B and hepatitis C among troops in Armed Forces

Suryam

Kathuria²,

Karunakaran³

2011

Medical Journal Armed Forces India

View full text Add to dashboard Cite

error taken at 5% and expected deviation as 1% for HBV and 0.5% for HCV, a minimum sample size of 1120 for HBV prevalence study and 1521 for HCV prevalence study was obtained. The sample was selected from the study population of army units located in the same station by the method of multistage random sampling.A detailed questionnaire was developed to study the risk factors for transmission of HBV and HCV infections and was administered to all serving personnel during sample collection. RESULTSA total of 1511 samples were collected from serving soldiers and all of these, were tested for HBsAg and anti-HCV.HBV: Overall point prevalence of HBsAg positivity in serving soldiers was found to be 1.25% (95% CI = 0.69%-1.81%).HCV: Of the 1151 samples tested for anti-HCV, not even one tested positive.Questionnaire on likely risk factors of HBV infection were administered to 1511 serving soldiers; completed questionnaires were received from 1262 persons and these were used for analysis of results.Mean age of the responders was 31.3 years with SD of 5.3 (range 19-46 years). Around 97% responders were personnel below officer rank and 95.6% were educated more than primary level (Table 1).History of having taken injections from civil medical practitioners was observed to be a highly significant risk factor (P < 0.001) with OR = 10.22 (95% CI = 3.29-30.68), thus indicating that injections from civil increased the risk of infection by ten times (Table 2). Past history of surgery (OR = 5.24), undergoing dental procedure (OR = 3.17), habit of sharing razors (OR = 9.09) were observed to have increased risk of HBV infection with, however the risk was not statistically significant in the study group. DISCUSSIONFindings of the study indicate that over all seroprevalence of HBV infection among population of Armed Forces was 1.25%. This is lower than 2.4% calculated as true prevalence in non-tribal

show abstract

Section: Methodsmentioning

confidence: 99%

A study of seroprevalence of hepatitis B and hepatitis C among troops in Armed Forces

Suryam

Kathuria²,

Karunakaran³

2011

Medical Journal Armed Forces India

View full text Add to dashboard Cite

show abstract

“…[7] Five percent of our patients were HBsAg positive, which is little higher than the value reported from the general population (2.97%) of Eastern India. [8] High seroprevalence of these infections may be due to lack of anti-HCV screening of blood products in the blood banks in Government and private sector, proper screening in the blood banks using Third and Fourth generation ELISA test is not done correctly or may be the kits labelled as ELISA are at fault. Professional donors are also on the increase than voluntary donors.…”

Section: Discussionmentioning

confidence: 99%

Epidemiology and impact on liver function of HepB, HepC, and HIV Infections in Multitransfused Thalassemic Patients in a Tertiary care Hospital in West Bengal, India

Biswas¹,

Roy²,

Basu³

2016

IOSR

View full text Add to dashboard Cite

show abstract

“…According to the WHO report on prevention of HBV in India, 10 HBsAg prevalence among general population ranges from 0.1% to 11.7%, being between 2% and 8% in most studies. [15][16][17][18][19][20][21][22][23][24][25] In the first large general population-based epidemiological study of HBV infection from India, Chowdhury et al 26 assessed the prevalence of serological markers of HBV infection in 19 villages in Birbhum district of West Bengal in Eastern India. Of the 7653 individuals who were included in the study, 227 (2.9%) tested positive for hepatitis B surface antigen (HBsAg), of whom 204 (90%) were HBeAg-negative and hepatitis B e antibody (anti-HBe)-positive, and 78% had normal alanine aminotransferase levels.…”

Section: Population Studiesmentioning

confidence: 99%

Tackling the Hepatitis B Disease Burden in India

Puri

2014

Journal of Clinical and Experimental Hepatology

121

View full text Add to dashboard Cite

Globally, approximately 240 people have been infected worldwide with hepatitis B Virus (HBV). India has approximately HBV carrier rate of 3.0% with a high prevalence rate in the tribal population. With a population of more than 1.25 billion, India has more than 37 million HBV carriers and contributes a large proportion of this HBV burden. While horizontal transmission in childhood appears to be a major route of transmission, the role of vertical transmission is probably underestimated. Blood transfusion and unsafe therapeutic injections continue to be important modes of transmission of HBV. There is a need for large field studies to better understand HBV epidemiology and identify high prevalence areas, and public health measures to prevent disease transmission and decrease the burden of the disease. ( J CLIN EXP HEPATOL 2014;4:312-319)

show abstract

Community‐based epidemiology of hepatitis B virus infection in West Bengal, India: Prevalence of hepatitis B e antigen‐negative infection and associated viral variants

Cited by 64 publications

References 36 publications

A study of seroprevalence of hepatitis B and hepatitis C among troops in Armed Forces

A study of seroprevalence of hepatitis B and hepatitis C among troops in Armed Forces

Epidemiology and impact on liver function of HepB, HepC, and HIV Infections in Multitransfused Thalassemic Patients in a Tertiary care Hospital in West Bengal, India

Tackling the Hepatitis B Disease Burden in India

Contact Info

Product

Resources

About