Herpes simplex encephalitis (HSE) is a leading cause of sporadic, nonepidemic viral encephalitis in children and adults. We report a very rare case of HSE with involvement of bilateral thalamus, putamen, upper pons and midbrain, with development of extrapyramidal symptoms which responded to corticosteroid therapy. A 15-mth-old female baby admitted with complaint of fever for 5 days and generalised tonic clonic seizure 10 hours before admission. On clinical examination patient was drowsy, temperature was 39.4 degrees C and vitals were stable with signs of increased intracranial tension. There were no signs of meningeal irritation. Patient gradually become unconscious in the next few hours and pupils were constricted bilaterally with development of atonia in all four limbs and neck muscles. Doll's eye phenomenon was absent.

To know the prevalence of HBV, HCV, and HIV infection in multitransfused thalassemic

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To study the effect of the supplementation of vitamin A along with standard dose of iron on hematopoiesis in children with documented iron deficiency anemia. Design: A hospital based prospective study. Place and Duration: Carried out for 6 months on children with documented iron deficiency anemia in OPD and indoor patients of the department of paediatric medicine, Medical College Kolkata. Methods: Thirty children (1-12 years age) presenting with iron deficiency anemia (hemoglobin less than 10g/dl, mean corpuscular volume (MCV) < 75fl, and serum iron < 55 mcg/dl) were studied in two groups of 15 each. Group I was supplemented with iron (ferrous sulphate 3 mg/kg/d) while group II in addition to iron was also supplemented with vitamin A (5000 IU/d).Collected data were expressed as mean +/-SE. Comparison of variables was done by using student t test or chi square test as applicable. p< 0.0001 was taken as statistically significant. Results: Hemoglobin concentration was found significantly increased after 4 weeks of iron supplementation. Rise in hemoglobin was comparatively more in-group II, as compared to group I, after 4 and 8 weeks. Conclusions: The result of this study suggests that supplementation of vitamin A improves hematopoiesis.