This study aimed to determine the presence of mammals in the nutmeg plantation, at Teluk Wondama Regency and Teluk Bintuni Regency. The researchwas conducted from 1 st to 7 th August 2019 and the study area was located in Werianggi, Werabur and Idor villages. The total area of research was 8,000 ha and the area was considered as nonforest area (the area for other purposes) in the form of primary dryland forests, secondary dryland forests and shrubs that included lowland forest ecosystems, karts hills and swamp ecosystems. The result revealed that the areas containedhigh diversity of mammals, both family and species. The diversity of mammals found included marsupialia, Rodentia, and Chiroptera with total of 38 species.22 of species were belong toendemic species of Papua and 6 species were protected species according to Indonesian Emvironment and Forestry Ministry Regulation number P.106 / 2018, and 5 species were included in the IUCN Red List category, and 2 species were listed in CITES Appendix II.