Comorbid depression in obsessive compulsive disorder (OCD): Symptomatic differences to major depressive disorder

Fineberg, Naomi; Fourie, Hannelie; Gale, Tim M.; Sivakumaran, T.

doi:10.1016/j.jad.2005.04.004

Cited by 33 publications

(20 citation statements)

References 9 publications

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“…Research examining the nature of these excessive cognitions supports their diagnostic specificity, as patients with OCD report more obsessional thoughts than patients with GAD, and patients with GAD report more preservative worry than patients with OCD (Brown et al, 1992;Brown et al, 1993). Although rumination has been investigated mostly in the context of depression (e.g., Nolen-Hoeksema, 1991); however, increased rumination has also been observed in OCD (Fineberg, Fourie, Gale, & Sivakumaran, 2005). Downloaded by [University of Nebraska, Lincoln] at 11:16 11 April 2015…”

Section: Discussionmentioning

confidence: 99%

Worry and Rumination in Generalized Anxiety Disorder and Obsessive Compulsive Disorder

Dar

Iqbal

2014

The Journal of Psychology

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Ample work has already been conducted on worry and rumination as negative thought processes involved in the etiology of most of the anxiety and mood related disorders. However, minimal effort has been exerted to investigate whether one type of negative thought process can make way for another type of negative thought process, and if so, how it subsequently results in experiencing a host of symptoms reflective of one or the other type of psychological distress. Therefore, the present study was taken up to investigate whether rumination mediates the relationship between worry and generalized anxiety disorder (GAD), and between worry and obsessive compulsive disorder (OCD) in two clinical groups. Self-report questionnaires tapping worry, rumination, generalized anxiety disorder (GAD), and obsessive compulsive disorder (OCD) were administered to a clinical sample of 60 patients aged 30-40. Worry, rumination, generalized anxiety disorder (GAD), and obsessive compulsive disorder (OCD) correlated substantially with each other, however, rumination did not mediate the relationship between worry and generalized anxiety disorder (GAD) and between worry and obsessive compulsive disorder (OCD). We also analyzed differences of outcome variables within two clinical groups. These results showed that worry and rumination were significantly different between GAD and OCD groups.

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Section: Discussionmentioning

confidence: 99%

Worry and Rumination in Generalized Anxiety Disorder and Obsessive Compulsive Disorder

Dar

Iqbal

2014

The Journal of Psychology

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“…However, examination of particular subtypes of OC and depressive symptoms may lead to increased specificity in predictions. Studies testing this proposal could build from cross-sectional research documenting that depressive symptoms are more strongly linked to obsessions than compulsions (Ricciardi & McNally, 1995), and from data showing that depression comorbid with OCD is less likely to be characterized by vegetative symptoms (e.g., sleep, appetite) than major depression alone (Fineberg, Fourie, Gale, & Sivakumaran, 2005). Therefore, separating obsessions versus compulsions and vegetative versus other symptoms may further clarify the vulnerability factors related to OC and depressive symptoms.…”

Section: Discussionmentioning

confidence: 99%

Predicting Changes in Obsessive Compulsive Symptoms Over a Six-Month Follow-Up: A Prospective Test of Cognitive Models of Obsessive Compulsive Disorder

et al. 2007

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Cognitive models of obsessive compulsive disorder (OCD) propose that OCD-related beliefs (e.g., inflated responsibility) and negative life events should predict changes in OC symptoms over time (The science and practice of cognitive behavior therapy. Oxford: Oxford University Press). However, very little research has tested these longitudinal predictions. The current study sought to replicate and extend findings by Coles and Horng (2006, Cognitive Therapy and Research, 30, 723-746) showing that OCD-related beliefs and negative life events significantly predicted changes in the frequency of OC symptoms over 6 weeks. Results of the current study, using a 6-month prospective longitudinal design, provided modest support for cognitive models of OCD. Negative life events significantly predicted residual change in both the frequency of, and distress associated with, OC symptoms. Initial OCD-related beliefs significantly predicted residual change in the distress associated with OC symptoms, but there was much additional variance to be accounted for. Additional data are presented that both examine the specificity of these predictors to changes in OC symptoms versus social anxiety and depressive symptoms, and explore particular types of life events in predicting symptom changes over time.

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“…As the strong relationship between anxiety and depression is well known (Mineka, Watson, & Clark, 1998), we are likely to find a relationship between anxiety and depression severity in OCD. Not unexpectedly, OCD patients with comorbid depression report more anxiety symptoms than their non-depressed counterparts (Fineberg, Fourie, Gale, & Sivakumaran, 2005;Overbeek et al, 2002). Similarly, Besiroglu et al (2007) found that comorbid generalized anxiety disorder significantly predicted the occurrence of major depressive disorder in OCD.…”

Section: Non-specific Factorsmentioning

confidence: 99%

Obsessive-compulsive disorder and comorbid depression: The role of OCD-related and non-specific factors

Yap

Mogan

Kyrios

2012

Journal of Anxiety Disorders

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Although comorbid depression is a predictor of poor treatment response in obsessive-compulsive disorder (OCD), there is limited understanding of factors that contribute to depression severity in OCD. The current study examines the influence of OCD-related factors (autogenous obsessions and obsessional beliefs) and non-specific factors (avoidance and anxiety) on depression severity in a sample of OCD patients. There were 56 participants with only OCD and 46 with OCD and comorbid depression. Self-report questionnaires measuring depression, OCD-related factors, and non-specific factors were completed. Although there were no significant differences between the two groups on these variables, depression severity was positively correlated with anxiety, avoidance, obsessional beliefs, and autogenous obsessions in the whole sample. When entered into a multiple regression model to predict depression severity, these factors accounted for 51% of the variance. While OCD-related factors remained significant predictors after controlling for non-specific factors, the non-specific factors made the most significant contributions to the model. Our findings suggest that in addition to dealing with autogenous obsessions, addressing anxiety and avoidance might lead to improvements in the treatment of OCD with comorbid depression.

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Comorbid depression in obsessive compulsive disorder (OCD): Symptomatic differences to major depressive disorder

Cited by 33 publications

References 9 publications

Worry and Rumination in Generalized Anxiety Disorder and Obsessive Compulsive Disorder

Worry and Rumination in Generalized Anxiety Disorder and Obsessive Compulsive Disorder

Predicting Changes in Obsessive Compulsive Symptoms Over a Six-Month Follow-Up: A Prospective Test of Cognitive Models of Obsessive Compulsive Disorder

Obsessive-compulsive disorder and comorbid depression: The role of OCD-related and non-specific factors

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