Comorbid depressive and anxiety symptoms and frailty among older adults: Findings from the West China health and aging trend study

Zhao, Wenchuan; Zhang, Yan; Liu, Xiaolei; Yue, Jirong; Hou, Lisha; Xia, Xin; Zuo, Zhengxing; Liu, Yang; Jia, Shuli; Dong, Birong; Ge, Ning

doi:10.1016/j.jad.2020.08.070

Cited by 65 publications

(79 citation statements)

References 45 publications

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“…Furthermore, the prevalence of depression in older adults in the Wuhan community was lower than that of older adults in western China, which was 19.6% ( Zhao et al, 2020 ), and higher than that of older adults in Jinan, Shandong Province, China, which was reported to be 11.6% ( Jin et al, 2020 ). Similar results were reported in a national cohort study of people aged over 65 years in Japan ( Shimada et al, 2019 ).…”

Section: Discussionmentioning

confidence: 84%

Analysis of Factors Associated With Depression in Community-Dwelling Older Adults in Wuhan, China

Liu

Peng

Zhu

et al. 2021

Front. Aging Neurosci.

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Objectives: This study aimed to identify the independent factors associated with depression in community-dwelling older adults in Wuhan, China.Methods: Four hundred and seventy older adults (aged ≥65 years) from four communities dwelling on Junshan Street in Wuhan, China were included in this study. Participants completed a questionnaire that asked questions pertaining to age, gender, educational level, income, living situation, care situation, social support, and social engagement. The 30-item Geriatric Depression Scale (GDS-30), the Fried frailty phenotype scale, the activities of daily living (ADL) scale, the mini nutritional assessment scale-short form (MNA-SF), and the Mini-cog scale were used to assess depression, frailty, self-care ability, malnutritional risk, and cognitive dysfunction, respectively. Differences in age, gender, educational level, income, living situation, care situation, social support, social engagement, ADL score, risk of malnutrition, frailty, and cognitive dysfunction between the non-depression (GDS-30 score <10 points) and depression groups (GDS-30 score ≥10 points) were compared using a chi-square test. Moreover, correlations between factors and depression were analyzed using Pearson’s correlation. Then, significant variables (p < 0.05) from the chi-square test were included in a multivariable logistic regression model to identify the independent factors associated with depression.Results: The incidence of depression among the participants was 14.04%. Age (p < 0.001), educational level (p < 0.001), living situation (p < 0.001), social support (p = 0.001), ADL score (p = 0.023), frailty (p < 0.001), and cognitive dysfunction (p < 0.001) were all significantly associated with depression, in which age, poor social support, frailty, and cognitive dysfunction were identified as independent factors.Conclusion: Improving social support and effective interventions for frailty and cognitive dysfunction may help relieve depression in community-dwelling older adults.

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Section: Discussionmentioning

confidence: 84%

Analysis of Factors Associated With Depression in Community-Dwelling Older Adults in Wuhan, China

Liu

Peng

Zhu

et al. 2021

Front. Aging Neurosci.

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“…According to the World Health Organization (WHO), depression is a prevalent mental disease that affects around 350 million people worldwide [ 5 ]. A study found that 8.7% of old adults had both depressive and anxious symptoms in China [ 6 ]. Psychological distress is a significant public health issue because it causes cognitive impairment, functional decline, physical disability, and increased health-care usage [ 7 , 8 ].…”

Section: Introductionmentioning

confidence: 99%

The association between sleep quality and psychological distress among older Chinese adults: a moderated mediation model

et al. 2022

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Background Previous research has found a link between sleep quality and psychological distress. However, the underlying mechanisms of this connection have still not been well explored. The aim of this study was to examine the roles of activities of daily living (ADL), physical activity, and perceived social support in the link between sleep quality and psychological distress among older adults. Methods Three thousand two hundred fifty valid individuals (aged 60 years or above) participated in face-to-face questionnaire-based surveys. Older individuals were assessed using the Pittsburgh Sleep Quality Index, Barthel Index, International Physical Activity Questionnaire, Perceived Social Support Scale, and Depression Anxiety Stress Scale-21. The PROCESS macro developed by Hayes was used to conduct moderated mediation analysis. Results In older adults, sleep quality had a substantial direct influence on psychological distress. ADL mediated the association between sleep quality and psychological distress. Physical activity significantly reduced ADL’s mediating influence on the relationship between sleep quality and psychological distress. Furthermore, perceived social support moderated the direct relationship between sleep quality and psychological distress, as well as the second half of the mediating effect of the ADL. Moreover, physical activity and perceived social support were preventive factors that might successfully mitigate the detrimental effects of poor sleep quality on ADL and psychological distress. Conclusions The findings contribute to existing understanding by clarifying the fundamental mechanisms that link sleep quality and psychological distress. These results may provide a valuable reference to the Chinese government for improving mental health in older individuals.

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“…Evidence on early screening of comorbid depressive and anxiety symptoms in mainland Chinese community populations is scarce. A limited number of studies are either based on elderly populations or in small sample community populations ( 11 , 12 ), underscoring the importance of conducting studies in large general populations. Furthermore, research in multicultural vulnerable populations is limited, especially in China, where is economically underdeveloped yet has undergone rapid urbanization in recent years.…”

Section: Introductionmentioning

confidence: 99%

Comorbid Depressive and Anxiety Symptoms and Their Correlates Among 93,078 Multiethnic Adults in Southwest China

Liu

Wangqing

Baima

et al. 2021

Front. Public Health

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Background: Depressive symptoms and anxiety symptoms commonly coexist and severely increases the disease burden worldwide. Little is known about the patterns and correlates of comorbid depressive and anxiety symptoms among the multiethnic populations of China.Methods: This population-based study investigated the comprehensive associations of comorbid depressive and anxiety symptoms with lifestyles, stressful life events, chronic diseases, and physical and mental well-being among 93,078 participants (37,193 men, 55,885 women) aged 30–79 years across seven ethnic groups in Southwest China. Multivariable logistic regression models were used to estimate associations.Results: Overall, 2.9% (2.1% in men and 3.5% in women) participants had comorbid depressive and anxiety symptoms; there was considerable heterogeneity among multiethnic populations. Participants with chronic diseases were more likely to have comorbidity than those without them; people with rheumatic heart disease reported the highest risk, with an odds ratio (OR) of 6.25 and 95% confidence interval (CI) of 4.06–9.62. Having experienced 3 or more stressful life events (OR, 8.43, 95% CI: 7.27–9.77), very poor self-rated health status (OR, 33.60, 95%CI: 25.16–44.87), and very unsatisfied life (OR, 33.30, 95% CI: 23.73–46.74) had strong positive associations with comorbid depressive symptoms and anxiety symptoms, with a dose-response relationship (P < 0.05). High frequency of physical activity had negative associations. All the associations were stronger than depressive symptoms alone or anxiety symptoms alone.Conclusions: Our findings emphasize the need to focus on the vulnerable ethnic groups with comorbid depressive and anxiety symptoms, ultimate for help early prevention and improvement of health equity in the underdevelopment and high urbanization areas.

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Comorbid depressive and anxiety symptoms and frailty among older adults: Findings from the West China health and aging trend study

Cited by 65 publications

References 45 publications

Analysis of Factors Associated With Depression in Community-Dwelling Older Adults in Wuhan, China

Analysis of Factors Associated With Depression in Community-Dwelling Older Adults in Wuhan, China

The association between sleep quality and psychological distress among older Chinese adults: a moderated mediation model

Comorbid Depressive and Anxiety Symptoms and Their Correlates Among 93,078 Multiethnic Adults in Southwest China

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