Comparative Antibacterial Effects of a Novel Copper and Silver- Based Core/Shell Nanostructure by Sonochemical Method

Abstract

In this study, the antibacterial effect of novel copper (Cu) and silver (Ag) metal-based coreshell nanostructures against Escherichia coli (E. coli-Gram negative) was investigated. The novel copper-and silver-based nanostructures were prepared separately by using nontoxic, biodegradable, and biocompatible biopolymers chitosan and guar gumpolyvinyl alcohol (GG-PVA), which were modified by inorganic phases SiO 2 and sepiolite. On the other hand, guar gum-PVA (GG-PVA) was modified by sepiolite, and this nanostructure was prepared only for silver. Besides, Cu was dispersed in a different biopolymer chitosan by sonochemical method in the presence and absence of SiO 2 .X-r a y photoelectron spectroscopy (XPS), scanning electron microscopy (SEM), and X-ray diffraction (XRD) techniques were used to characterize the surface chemistry and morphology of the core/shell nanostructure. Nanoscale zero-valent Cu (NZVCu) was found under thin CuO film according to the XPS results. SEM images showed that spherical Cu/CuO@SiO 2 nanostructures (100 nm) were homogenously dispersed in the chitosan by using sonochemical method. Antibacterial property of the core-shell nanostructures was analyzed by well-diffusion method against Escherichia coli (E. coli-Gram negative). Cu/CuO@SiO 2 nanostructures were found very effective against the E. coli due to high ratio of NZVCu in the nanostructure.

Microfluidics for core–shell drug carrier particles – a review

“…Due to the high ratio of NZVCu in the nanostructure, Cu/CuO@SiO 2 nanostructures are very effective against E. coli . 134 …”

Impact of NH4OH treatment on the ion exchange and pore characteristics of a metakaolin-based geopolymer

“…14 Similar procedures have been shown to be applicable to geopolymer catalysts. 13 The effect of such treatments on the geopolymer properties has been studied to some extent by diffuse reectance infrared Fouriertransform (DRIFT) spectroscopy for monitoring the success of the NH 4 + ion-exchange, 15 and 27 Al and 29 Si magic angle spinning nuclear magnetic resonance (MAS NMR), 16 which provide information about structural changes caused by the treatment. However, more information about the impact of such treatments on modifying the chemical structure, particle morphology, and pore properties, importantly poreconnectivity, is still needed.…”