Comparative antimicrobial studies on plant species known as ’Pasak Bumi': Eurycoma longifolia Jack., Rennelia elliptica Korth. and Trivalvaria macrophylla miq.

Abstract

Pasak Bumi is a local name for a medicinal plant in Kalimantan, Indonesia. It is a famous medicinal plant and commonly used in traditional medicine as an aphrodisiac, as well as in the treatment of malaria. Pasak Bumi is a commercial name for Eurycoma longifolia (Simaroubaceae) plant species. Besides Eurycoma longifolia there are two other plant species also known locally as Pasak Bumi, Rennelia elliptica (Rubiaceae) and Trivalvaria macrophylla (Annonaceae). This study was performed to investigate the antimicrobial activities of the different species of Pasak Bumi and its total phenol contents. The antimicrobial activity of the ethanol extract was determined using the Agar Well Diffusion method at various concentrations while the phenol content was determined by the Folin - Ciocalteu method. The results of the ethanol extract from the different root showed that the T. macrophylla had the highest phenol content, and the highest activity index (AI) was found in the E. longifolia (0.96 at 1000 µg concentration). The results of this study show that the three different Pasak Bumi have potential as antimicrobials against oral pathogen; 1 yeast: Candida albicans, and 3 bacterias: Staphylococcus aureus, Streptococcus mutans, and Streptococcus sobrinus.

A Systematic Review on Antimicrobial and Antiparasitic Activity of Eurycoma longifolia Jack (Tongkat Ali)

“…Kuspradini et al [ 23 ] evaluated comparative antimicrobial studies on E. longifolia Jack, Rennellia elliptica Korth, and Trivalvaria macrophylla Miq. against C. albicans , S. aureus , S. mutans , and Streptococcus sobrinus.…”

Review: The conservation of Tengger indigenous people's traditional knowledge of biological natural resource‐based disease treatments

“…Modern research proves the presence of antimicrobial, antioxidant, anti-inflammatory, anti-anxiety, anti-lipid, anti-diabetic, and anti-cancer properties (Rather et al 2012. Kooti et al 2015Kuspradini et al 2019;Kuspradini et al 2020). Meanwhile, A. calamus has long been applied in traditional medicine, and also possesses anticarcinogenic and anti-angiogenic features (Imam et al 2013;Haghighi et al 2017).…”

BAKTERI ENDOFIT YANG DIISOLASI DARI AKAR <em>Eurycoma longifolia</em> DAN POTENSINYA SEBAGAI PENGENDALI JAMUR PATOGEN TANAMAN

“…Bahan aktif tersebut dapat ditemukan pada seluruh bagian tanaman dengan kadar yang bervariasi. Khanam et al (2015) dan Kuspradini et al (2019) mengemukakan bahwa ekstrak tanaman pasak bumi menunjukkan aktivitas antimikrob. Senyawa aktif yang terdapat dalam tanaman pasak bumi sebagian besar dimanfaatkan dalam bidang kesehatan, walaupun senyawa canthin-6one dan alkaloid β-carboline yang terkandung dapat digunakan sebagai insektisida pengusir serangga dan herbivora (Chua et al 2011).…”