2003
DOI: 10.1016/s0278-6915(03)00216-3
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Comparative assessment of gastrointestinal irritant potency in man of tin(II) chloride and tin migrated from packaging

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Cited by 53 publications
(29 citation statements)
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“…A limited number of case reports of acute gastrointestinal disorders after consumption of food containing high concentrations (700 ppm or above) of tin have been reported, but there is little evidence for an association between the consumption of food containing tin at concentrations up to 200 ppm and significant acute adverse gastrointestinal effects (32,33).…”
Section: Foodmentioning
confidence: 99%
“…A limited number of case reports of acute gastrointestinal disorders after consumption of food containing high concentrations (700 ppm or above) of tin have been reported, but there is little evidence for an association between the consumption of food containing tin at concentrations up to 200 ppm and significant acute adverse gastrointestinal effects (32,33).…”
Section: Foodmentioning
confidence: 99%
“…Only limited reports are available on the toxicological effects of inorganic tin as present in canned foods, resultant from dissolution on the tin coating [1]. The main potential hazard from acute ingestion seems to be gastric irritation in some individuals exposed to high levels [2]. The maximum limit of 250 mg kg −1 for tin in canned foods and 150 mg kg −1 for tin in canned beverages was recommended by World Health Organization [3].…”
Section: Introductionmentioning
confidence: 99%
“…At pH >2, Sn(II) forms Sn(OH) 2 , which has low solubility under anoxic conditions, whereas Sn(IV) presents in form of Sn(OH) 4 under oxic conditions at lower pHs than 8.0 (Kassoufab et al 2013). Tin is widely used for the production of beverage cans in food industry and as a corrosion protective coating component (Perring and Basic-Dvorzak 2002;Boogaard et al 2003). However, the used tin for packaging of food and beverage samples dissolves into the samples depending on the quantity of food ingested and pH, oxidation state, extent of complexation or adsorption, and solubility (Blunden and Wallace 2003).…”
Section: Introductionmentioning
confidence: 99%
“…However, the used tin for packaging of food and beverage samples dissolves into the samples depending on the quantity of food ingested and pH, oxidation state, extent of complexation or adsorption, and solubility (Blunden and Wallace 2003). According to EC 1881/2006, maximum limit for tin (in mg kg −1 wet weight) are as follows: (i) 200 mg kg −1 in canned foods other than beverages, (ii) 100 mg kg −1 in canned beverages including fruit and vegetable juices, and (iii) 50 mg kg −1 in baby food (Boogaard et al 2003;Abedi and Ebrahimzadeh 2013). Due to the acidity, presence of oxidizing reagents, food matrix, and storage conditions such as temperature/time, affect the rate of dissolution of tin into canned food and beverage (Perring and Basic-Dvorzak 2002;Sunday et al 2013;Morte et al 2012), the level of tin may be greater than the amounts above.…”
Section: Introductionmentioning
confidence: 99%