1985
DOI: 10.1128/mmbr.49.3.298-337.1985
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Comparative biology of intracellular parasitism.

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Cited by 311 publications
(182 citation statements)
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References 262 publications
(397 reference statements)
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“…Many bacterial species are capable of invading and multiplying in mammalian cells (Moulder, 1985). Currently available data suggest that these bacteria have evolved quite (C/ Oxford University Press different strategies for entry into host cells, all involving some form of induced phagocytosis (Finlay and Falkow, 1989;Falkow, 1991).…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…Many bacterial species are capable of invading and multiplying in mammalian cells (Moulder, 1985). Currently available data suggest that these bacteria have evolved quite (C/ Oxford University Press different strategies for entry into host cells, all involving some form of induced phagocytosis (Finlay and Falkow, 1989;Falkow, 1991).…”
Section: Introductionmentioning
confidence: 99%
“…Once within the infected cell, two distinct modes of intracellular survival for such microorganisms have been distinguished. Some invasive microorganisms like Salmonella or Yersinia species remain and multiply within a membrane bound phagocytic vacuole (Moulder, 1985;Finlay and Falkow, 1989). Intercellular spread of such bacteria may follow routes utilized by intracellular organelles by transcytosing from the apical to the basal pole of these cells as has been suggested for example for Salmonella cholerasuis (Finlay and Falkow, 1988).…”
Section: Introductionmentioning
confidence: 99%
“…Secondary macrophage dysfunction may also be associated with various clinical conditions such as viral infection, cancer, acidosis, pulmonary edema and uremia. In addition, various microorganisms have developed strategies to resist or even use macrophages to persist and multiply intracellularly [12]. Macrophage and neutrophil dysfunction may also be found in some rare genetic disorders (e.g.…”
Section: The Mucociliary Escalatormentioning
confidence: 99%
“…Target cell lysis by itself could be important for those intracellular bacteria which exclusively depend on an intracellular habitat, like M . leprae [54]. Since LM can replicate in the extracellular milieu, for this pathogen direct inhibitory effects appear less important.…”
Section: It Has Been Demonstrated That Cytolytic T Cells Inducementioning
confidence: 99%