Comparative Development of the Mammalian Yolk Sac

King, Barry F.; Enders, Allen C.

doi:10.1007/978-3-642-77852-0_1

Cited by 14 publications

(13 citation statements)

References 100 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Agents that cause visceral yolk sac dysfunction during organogenesis can result in embryotoxicity and its damage leads to embryonic malformation [26]. In virtually all eutherian species studied, there is evidence of synthetic activity by the yolk sac and it serves as hematopoietic organ in all mammalian species studied (reviewed by King & Enders [22]). These synthetic activities may occur throughout gestation, influencing implantation as well as embryonic and fetal growth (reviewed by King & Enders [22]).…”

Section: Introductionmentioning

confidence: 99%

“…In virtually all eutherian species studied, there is evidence of synthetic activity by the yolk sac and it serves as hematopoietic organ in all mammalian species studied (reviewed by King & Enders [22]). These synthetic activities may occur throughout gestation, influencing implantation as well as embryonic and fetal growth (reviewed by King & Enders [22]). In marsupials, rstb.royalsocietypublishing.org Phil Trans R Soc B 368: 20120151 the yolk sac forms the definitive placenta, being responsible for physiological exchange, biosynthesis and endocrinology [17,20,27,28].…”

Section: Introductionmentioning

confidence: 99%

“…However, the nutritive, biosynthetic and hematopoietic functions of the human yolk sac are not new inventions specific to humans, but ancestral features shared with other viviparous mammals. The rodent visceral yolk sac (inverted yolk sac) is an important organ of maternal-embryonic exchange of amino acids, transferrin, vitamin B 12 , calcium and other ions [22,23]. The rodent visceral yolk sac is also the route by which passive immunity (immunoglobulins) is passed to the embryo [24,25].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

The origin and evolution of genomic imprinting and viviparity in mammals

Renfree

Suzuki

Kaneko-Ishino

2013

Phil. Trans. R. Soc. B

157

134

View full text Add to dashboard Cite

Genomic imprinting is widespread in eutherian mammals. Marsupial mammals also have genomic imprinting, but in fewer loci. It has long been thought that genomic imprinting is somehow related to placentation and/or viviparity in mammals, although neither is restricted to mammals. Most imprinted genes are expressed in the placenta. There is no evidence for genomic imprinting in the egg-laying monotreme mammals, despite their short-lived placenta that transfers nutrients from mother to embryo. Post natal genomic imprinting also occurs, especially in the brain. However, little attention has been paid to the primary source of nutrition in the neonate in all mammals, the mammary gland. Differentially methylated regions (DMRs) play an important role as imprinting control centres in each imprinted region which usually comprises both paternally and maternally expressed genes (PEGs and MEGs). The DMR is established in the male or female germline (the gDMR). Comprehensive comparative genome studies demonstrated that two imprinted regions, PEG10 and IGF2-H19, are conserved in both marsupials and eutherians and that PEG10 and H19 DMRs emerged in the therian ancestor at least 160 Ma, indicating the ancestral origin of genomic imprinting during therian mammal evolution. Importantly, these regions are known to be deeply involved in placental and embryonic growth. It appears that most maternal gDMRs are always associated with imprinting in eutherian mammals, but emerged at differing times during mammalian evolution. Thus, genomic imprinting could evolve from a defence mechanism against transposable elements that depended on DNA methylation established in germ cells.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The origin and evolution of genomic imprinting and viviparity in mammals

Renfree

Suzuki

Kaneko-Ishino

2013

Phil. Trans. R. Soc. B

157

134

View full text Add to dashboard Cite

show abstract

“…The situation in ruminants is comparable to that in bats, where the yolk sac can form a gland-like structure (Carter and Mess, 2008). Similarly, a free-floating yolk sac is found in human and other higher primates, but as a rule it disappears later in gestation (Enders and King, 1993).…”

Section: Yolk Sac and Choriovitelline Placentationmentioning

confidence: 77%

“…Where this is complete it results in the endoderm facing the uterine cavity. The inverted yolk sac of rodents is an important conduit for histotrophe and maternal-fetal transfer of antibodies (King and Enders, 1993;Carter, 2015).…”

Section: Yolk Sac and Choriovitelline Placentationmentioning

confidence: 99%

Advances in flow cytometry in basic and applied equine andrology

2017

View full text Add to dashboard Cite

Molecular phylogenetics has made a substantial contribution to our understanding of the relationships between mammalian orders and has generated trees that can be used to examine the evolution of anatomical and physiological traits. We here summarize findings on fetal membranes and placentation in Ferungulata, a clade comprising carnivores, pangolins, and even-and odd-toed ungulates. Their early ontogeny shows several conserved traits such as superficial attachment of the blastocyst, amnion formation by folding, a large allantoic sac and a temporary yolk sac placenta. In contrast, several characters of the chorioallantoic placenta are derived, including the diffuse and cotyledonary placental types in ungulates and zonary placenta in carnivores, specializations of the interhaemal barrier, the presence of areolae or haemophagous regions and lack of stromal decidual cells. Ungulates produce large amounts of placental proteins including placental lactogens and pregnancy-associated glycoproteins. Evolutionary innovations of the placental system may contribute to the high diversity of lifestyles within Ferungulata and be linked to the evolution of highly precocial offspring in ungulates.

show abstract

Origin of extraembryonic mesoderm in experimental animals: Relevance to chorionic mosaicism in humans

et al. 1993

View full text Add to dashboard Cite

Confined chorionic mosaicism, a discordance in the karyotype between the fetus and placenta, occurs in 1% of chorionic villus sampling (CVS) cases. While the cytogenetic discrepancies occurring between different fetal tissues may pose clinical dilemmas, they can also be viewed as a natural experiment to determine early cell lineage relationships in the human. We reviewed extensive data in experimental animals to define the origin of the human extraembryonic mesoderm. The extraembryonic mesoderm in humans is an important component of the CVS culture preparation. Previously, the extraembryonic mesoderm was thought to originate in the cytotrophoblast or primitive streak. More recent evidence supports its origin from the yolk sac, which does not always correlate with the fetal karyotype. We formulated a model of early human cell lineage and employed it to clarify clinical cases of chorionic mosaicism in two large published studies.

show abstract

Comparative Development of the Mammalian Yolk Sac

Cited by 14 publications

References 100 publications

The origin and evolution of genomic imprinting and viviparity in mammals

The origin and evolution of genomic imprinting and viviparity in mammals

Advances in flow cytometry in basic and applied equine andrology

Origin of extraembryonic mesoderm in experimental animals: Relevance to chorionic mosaicism in humans

Contact Info

Product

Resources

About