Comparative Effect of Encapsulated and Nonencapsulated Probiotic Bacteria on Broiler Production Performance

16S rRNA gene sequencing reveals the effect of fluoxetine on gut microbiota in chronic unpredictable stress-induced depressive-like rats

“…The GABA(A) receptor complex is a target of FLX [ 30 ], and chronic administration of FLX was found to enhance hippocampal excitatory synaptic transmission in rats through synaptic strengthening, indicating its benefit for the treatment of long-term depression [ 25 ]. Our present study revealed that the proportions of four probiotic bacteria, namely L. gasseri [ 31 ], L. intestinalis [ 32 ], L. lactis [ 33 ] and B. animalis [ 34 ] were not influenced by chronic stress alone or in combination with chronic FLX administration, suggesting that the latter was ineffective in changing the levels of probiotics. It is possible that the levels of these probiotic bacteria were not affected by chronic FLX treatment per se, but by some other mechanism involved in bodily self-defence against chronic stress in rats.…”