Comparative effectiveness of team-based care with a clinical decision support system versus team-based care alone on cardiovascular risk reduction among patients with diabetes: Rationale and design of the D4C trial

Shi, Xiulin; He, Jiang; Lin, Mingzhu; Liu, Changqin; Yan, Bing; Song, Haiqu; Wang, Caihong; Xiao, Fangsen; Huang, Peiying; Wang, Liying; Li, Zhibin; Huang, Yinxiang; Zhang, Mulin; Chen, Chung-Shiuan; Obst, Katherine; Li, Weihua; Yang, Shuyu; Yao, Guanhua; Li, Xuejun

doi:10.1016/j.ahj.2021.04.009

Cited by 9 publications

(5 citation statements)

References 61 publications

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“…22 The other study used community approaches as secondary prevention for reducing worse conditions. 23 The findings indicated that 60.3% of stroke patients who received community-based interventions exhibited a reduction in the severity of their condition. The efficacy ascribed to the emphasis on secondary prevention was evidenced by a study done in Surakarta.…”

Section: Methods Study Designmentioning

confidence: 97%

Prevention Program for People Living with Stroke in Low and Middle-Income Country: A Systematic Review

Lahdji,

Pudjonarko,

Shaluhiyah

2024

JPKI

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Background: Non-communicable diseases (NCDs) are the primary factors responsible for mortality and impairment on a global scale. By 2030, it is estimated that non-communicable diseases will comprise 80% of the global population. According to the World Health Organization (WHO), the risk of stroke will grow by 50% for the entire global population by 2022. Currently, it is projected that 1 in 4 individuals will suffer from a strokeMethod: This review was reported using the “Preferred Reporting Items for Systematic Reviews and Meta-Analysis” guideline and written using the “Synthesis without Meta-Analysis” method. The included studies for this review followed several criteria, including randomized controlled trials (RCT), English and Bahasa articles, using population was people living with stroke, intervention was any prevention and disability limitation, and outcomes were prevention measurements (primary, secondary, and tertiary prevention).Results: The study yielded multiple efficacious and streamlined preventive interventions implemented for stroke patients. Emphasizing risk factors as the main strategy for preventing health issues, using pharmacological treatments such as polypill, aspirin, and vitamins as a supplementary measure under the guidance of medical physicians and cardiologists. In addition, tertiary preventive initiatives encompass more than just administering drug treatment; they also require adherence to pharmaceutical protocols

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Section: Methods Study Designmentioning

confidence: 97%

Prevention Program for People Living with Stroke in Low and Middle-Income Country: A Systematic Review

Lahdji,

Pudjonarko,

Shaluhiyah

2024

JPKI

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“…There remains a main issue that the team-based approach is hard to replicate in the community; efforts have been made to develop protocols and guidelines that can facilitate the implementation of interdisciplinary team care of patients with T2DM in community settings. A recently published study design called the Diabetes Complication Control in Community Clinics (D4C) study is a cluster-randomized trial conducted among 38 community health centers in China [ 70 ]. In addition to the members usually included in DM management, such as endocrinologists, cardiologists, and primary care physicians, the study design proposes to add a clinical decision support system that integrates guideline-based treatment algorithms for glycemic, blood pressure, and lipid control, together with a patient’s medical history and insurance policy [ 70 ].…”

Section: The Team-based Approach To Diabetes Managementmentioning

confidence: 99%

“…A recently published study design called the Diabetes Complication Control in Community Clinics (D4C) study is a cluster-randomized trial conducted among 38 community health centers in China [ 70 ]. In addition to the members usually included in DM management, such as endocrinologists, cardiologists, and primary care physicians, the study design proposes to add a clinical decision support system that integrates guideline-based treatment algorithms for glycemic, blood pressure, and lipid control, together with a patient’s medical history and insurance policy [ 70 ]. Although the results of the D4C trial have not been published yet, it presents a cluster-randomized trial design that provides a roadmap for team-based primary care in community clinics in Asia.…”

Section: The Team-based Approach To Diabetes Managementmentioning

confidence: 99%

Team-Based Approach to Reduce Malignancies in People with Diabetes and Obesity

et al. 2023

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Purpose of Review Numerous observations have indicated an increased risk of developing various types of cancers, as well as cancer-related mortality, among patients with diabetes and obesity. The purpose of this review is to outline multiple-cancer screening among these patients through a team-based approach and to present the findings of a pioneering integrated care program designed for patients with obesity with a specific emphasis on cancer prevention. Recent Findings A community-based multi-cancer prevention program, which provides all services in one location and utilizes team-based approaches, is reported to be feasible and has the potential to enhance the uptake rate of multiple cancers screening among patients with diabetes and obesity. Summary The team-based approach is a commonly utilized method for managing patients with diabetes, obesity, and cancer, and has been shown to be efficacious. Nevertheless, research on team-based cancer screening programs for patients with diabetes and obesity remains limited. Providing a comprehensive screening for colorectal, prostate, and breast cancer, as well as metabolic syndrome, during a single clinic visit has been proven effective and well-received by participants.

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“…( 1 ). Research has shown that strengthening control over risk factors and reducing exposure to risk factors can significantly reduce the incidence of CVD, as well as mortality from it ( 2 – 4 ). However, even with tight control over traditional risk factors, a considerable proportion of patients remain vulnerable to high risks of cardiovascular events.…”

Section: Introductionmentioning

confidence: 99%

Targeting Trimethylamine N-Oxide: A New Therapeutic Strategy for Alleviating Atherosclerosis

Jing

Zhang

Xiang

et al. 2022

Front. Cardiovasc. Med.

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Atherosclerosis (AS) is one of the most common cardiovascular diseases (CVDs), and there is currently no effective drug to reverse its pathogenesis. Trimethylamine N-oxide (TMAO) is a metabolite of the gut flora with the potential to act as a new risk factor for CVD. Many studies have shown that TMAO is involved in the occurrence and development of atherosclerotic diseases through various mechanisms; however, the targeted therapy for TMAO remains controversial. This article summarizes the vital progress made in relation to evaluations on TMAO and AS in recent years and highlights novel probable approaches for the prevention and treatment of AS.

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Comparative effectiveness of team-based care with a clinical decision support system versus team-based care alone on cardiovascular risk reduction among patients with diabetes: Rationale and design of the D4C trial

Cited by 9 publications

References 61 publications

Prevention Program for People Living with Stroke in Low and Middle-Income Country: A Systematic Review

Prevention Program for People Living with Stroke in Low and Middle-Income Country: A Systematic Review

Team-Based Approach to Reduce Malignancies in People with Diabetes and Obesity

Targeting Trimethylamine N-Oxide: A New Therapeutic Strategy for Alleviating Atherosclerosis

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