Comparative efficacy of a herbal and a non‐herbal dentifrice on dentinal hypersensitivity: a randomized, controlled clinical trial

Kumari, Minal; Naik, Savitha B.; Martande, Santosh S.; Pradeep, A.R.; Singh, Priyanka

doi:10.1111/jicd.12133

Cited by 9 publications

(8 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Interestingly, some studies reported significant DH reduction in groups absent from active principle, indicating the possible contribution of the placebo effect or even the Hawthorne effect on the action of desensitisers . In the case of the placebo effect, the participants would present a physiological response after administration of an inert agent, such as saline solution.…”

Section: Discussionmentioning

confidence: 99%

“…In this review, three studies were included that refer to a statistical improvement in DH with the use of herbal dentifrices, two of which refer to the agent Spinacia oleracea. 79,92,93 However, the presence of potassium nitrate in the composition of the described dentifrices does not allow a correct understanding of the true nature of the desensitising effect of Spinacia oleracia in the treatment of DH, since this effect may be due to the nitrate in the composition of the product.…”

Section: Percentage Of Dh Reduction Between Baseline and Final Follow-upmentioning

confidence: 99%

“…The existence of these placebo control groups may give additional information about the efficacy of the agents tested, allowing a better interpretation of the results; however, the use of negative controls in DH trials is controversial, since some authors support that, for ethical reasons, treatments without an active ingredient should not be performed. In some of the studies, positive control groups with fluoride dentifrices were used 29,35,46,51,[62][63][64]68,74,81,88,90,92,94. These pastes should not beused as a negative control, as stated by some authors, as they may have different fluorides or other agents, and it is not clear which fluoride concentration is effective in the treatment of DH.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Evaluation of the efficacy of dentin hypersensitivity treatments—A systematic review and follow‐up analysis

Marto

Paula

Nunes

et al. 2019

J of Oral Rehabilitation

View full text Add to dashboard Cite

Objectives To compare the treatments used to treat dentin hypersensitivity (DH), based on its efficacy and effect duration. Methods Medline/PubMed, Cochrane Library, EMBASE and ClinicalTrials were searched for articles published between 1 January 2008 and 14 November 2018, in English, Portuguese or Spanish, reporting clinical trials, completed and with results. This systematic review protocol was registered in PROSPERO, number CRD42019121986. Results Seventy‐four randomised clinical trials were included in the systematic review, reporting patients from 16 to 65 years old, with a clinical diagnosis of DH, that evaluate the efficacy of a desensitising product, compared to pre‐treatment, used the evaporative method stimulation and the visual analogue scale. These studies evaluated 5366 patients and at least 9167 teeth. Seven follow‐up periods were considered corresponding to an immediate, medium or long‐time effect. Sixty‐six studies were included in the quantitative synthesis. Glutaraldehyde with HEMA, glass ionomer cements and Laser present significant immediate (until 7 days) DH reduction. Medium‐term (until 1 month) reduction was observed in stannous fluoride, glutaraldehyde with HEMA, hydroxyapatite, glass ionomer cements and Laser groups. Finally, long‐term significant reduction was seen at potassium nitrate, arginine, glutaraldehyde with HEMA, hydroxyapatite, adhesive systems, glass ionomer cements and LASER. Conclusions All active ingredients show efficacy in DH reduction in different follow‐up times. Only in‐office treatments are effective in immediate DH reduction, maintaining its efficacy over time. For long‐time effects, at‐home treatments can also be used. More standardised evaluation protocols should be implemented to increase the robustly of the results.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Percentage Of Dh Reduction Between Baseline and Final Follow-upmentioning

confidence: 99%

mentioning

confidence: 99%

See 1 more Smart Citation

Evaluation of the efficacy of dentin hypersensitivity treatments—A systematic review and follow‐up analysis

Marto

Paula

Nunes

et al. 2019

J of Oral Rehabilitation

View full text Add to dashboard Cite

show abstract

“…So far, many toothpastes with the various herbal structures are developed, and their capability in the tubule occlusion are reported (Kaur, Paul, Rathee, & Arora, 2020;Kumari, Naik, Martande, Pradeep, & Singh, 2016;Vajrabhaya, Korsuwannawong, Harnirattisai, & Teinchai, 2016). Moreover, in an in vitro study, the effectiveness of the toothpastes having silica as abrasives in tubular occlusion process was analyzed (Addy & Mostafa, 1989).…”

Section: Resultsmentioning

confidence: 99%

Evaluating the antibacterial effect of synthesized herbal toothpastes and their efficacy for dentine tubule occlusion: Scanning electron microscopy and energy‐dispersive X‐ray spectroscopy analysis

Mousavi

Ganjovi

Eskandarizadeh

et al. 2021

Microscopy Res & Technique

View full text Add to dashboard Cite

The tubule occlusion of two newly developed herbal toothpastes was examined. They were prepared based on the mixture of pomegranate peel and Equisetum arvense extracts with strontium acetate. The antimicrobial activity of pomegranate peel and E. arvense were determined using minimum inhibitory concentration (MIC). Then, 30 mid-coronal dentin discs from the human third molars were etched for 30 s with the lemon juice (pH = 2.4). The specimens divided into the three groups. While the control group had 6 specimens, Groups 1 and 2 were including 12 specimens. Group 1 brushed with toothpaste containing 10% strontium acetate and 5% hydroalcoholic extracts of pomegranate peel, and Group 2 brushed with 5% strontium acetate, 5% hydroalcoholic extracts of E. arvense, and 5% hydroalcoholic extracts of pomegranate peel. Brushing was simulated for 6 months with 2 N loading. Then, 50% of discs in each group were immersed in lemon juice for 1 min. Moreover, specimens in control group were brushed with distilled water. Finally, all 30 discs were analyzed using scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDXS).The occluded dentin tubules were counted and statistically evaluated. It was found that the number of open dentin tubules decreases significantly after brushing with both tested toothpastes compared with control group (p < .001). Moreover, a significant difference was observed between two toothpastes before and after acid immersion process (p < .001). The SEM micrographs confirmed the dentin tubule occlusion of both herbal dentifrices. Besides, EDXS analysis approved the strontium and silica presence on the dentin tubules for the toothpaste which was based on E. arvense.

show abstract

“…TG 3 group showed effective results but slowly that can be observed from Tables 1–5. Kumari et al 2016[31] compared the efficacy of herbal and nonherbal dentifrices against DH on 145 patients having DH and were randomly divided into three groups: placebo, herbal, and nonherbal groups. The result showed herbal dentifrices was more effective than the nonherbal group.…”

Section: Discussionmentioning

confidence: 99%

Comparative evaluation of neodymium-doped yttrium aluminum garnet laser with nanocrystalline hydroxyapatite dentifrices and herbal dentifrices in the treatment of dentinal hypersensitivity

Yadav

Verma

Tiwari

2019

Natl J Maxillofac Surg

View full text Add to dashboard Cite

Background: The aim of this study was to compare and evaluate the efficacy of neodymium-doped yttrium aluminum garnet laser with and without herbal and nanohydroxyapatite dentifrices in management of dentinal hypersensitivity (DH). Materials and Methods: A total of 180 patients who responded to air-blast test and cold-water test using verbal rating scale (VRS) were included in this study. The patients were randomly assigned to six groups ( n = 30): control group (CG), scaling and root planning (SRP) + nanocrystalline hydroxyapatite dentifrices, SRP + nanocrystalline hydroxyapatite dentifrices + laser, SRP + herbal dentifrices, SRP + herbal dentifrices + laser, and SRP + laser. Each group was evaluated at baseline, 1 week, 1 month, and 6 months. In every visit of each patient, their clinical examination was done. Results: Among all groups’, repeated ANOVA measures and Kruskal–Wallis test was performed in which laser groups showed maximum reduction in DH in all indices while the CG showed minimum reduction in DH. The VRS values showed maximum reduction in SRP + nanocrystalline hydroxyapatite dentifrices + laser group with mean of 0.3 ± 0.5 and minimum reduction in CG with mean of 3.0 ± 0.5 ( P < 0.001). Conclusion: Among all the groups, SRP + Nanocrystalline hydroxyapatite + Laser can be an effective treatment modality for DH.

show abstract

Comparative efficacy of a herbal and a non‐herbal dentifrice on dentinal hypersensitivity: a randomized, controlled clinical trial

Abstract: The herbal dentifrice showed comparable results to the non-herbal dentifrice and can be recommended for the treatment of DH.

Cited by 9 publications

References 33 publications

Evaluation of the efficacy of dentin hypersensitivity treatments—A systematic review and follow‐up analysis

Evaluation of the efficacy of dentin hypersensitivity treatments—A systematic review and follow‐up analysis

Evaluating the antibacterial effect of synthesized herbal toothpastes and their efficacy for dentine tubule occlusion: Scanning electron microscopy and energy‐dispersive X‐ray spectroscopy analysis

Comparative evaluation of neodymium-doped yttrium aluminum garnet laser with nanocrystalline hydroxyapatite dentifrices and herbal dentifrices in the treatment of dentinal hypersensitivity

Contact Info

Product

Resources

About