Comparative gender differences in local and systemic concentrations of pro‐inflammatory cytokines in rats with experimental periodontitis

Abstract

Our study suggests that females with periodontal disease have a greater risk for inflammatory-based systemic diseases than males.

Endothelial dysfunction in rats with ligature-induced periodontitis: Participation of nitric oxide and cycloxygenase-2-derived products

“…the systemic vasculature, as this bacteria has been found in atheroma plaques (Haraszthy et al, 2000) and thrombi from patients with acute myocardial infarction (Ohki et al, 2012). In addition, and strengthening the validity of the animal model used in this study, increased nitration of cardiac proteins (Ma, Guo, You, Xia, & Yan, 2011) and enhanced lipid deposits in aorta (Bain et al, 2009) have been detected in rats seven days after ligature induced-periodontitis.…”

Independent determinants of periodontitis in Yemeni adults: A case‐control study

“…It was claimed that females care and comply more than males do with regard to oral health behaviours . However, gender‐specific differences in prevalence and severity of periodontitis might be beyond health behaviour; sex hormones were reported to be possibly involved . Overall, such a difference remains controversial so far .…”

Influence of different durations of estrogen deficiency on alveolar bone loss in rats

“…16 Therefore, ovariectomy-induced osteopenia in the rat produces skeletal responses similar to those in post-menopausal women. 17 A morphometric analysis of defleshed jaws [11][12][13]18,19 was applied to assess the amount of periodontal bone in the rats. This analysis is reproducible and can discriminate among experimental groups.…”