Comparative genomics and evolution of the HSP90 family of genes across all kingdoms of organisms

Chen, Bin; Zhong, Daibin; Monteiro, Antónia

doi:10.1186/1471-2164-7-156

Cited by 286 publications

(265 citation statements)

References 68 publications

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“…Much of the complexity of modern eukaryotic cells arises from this divided ancestry involving gene movement between genomes and the evolution of mechanisms for targeting gene products to the correct cellular compartment. Even individual enzymatic pathways or functional systems can be encoded by complex combinations of genes with different histories of direct horizontal transfer, transfer through symbiosis, or vertical inheritance (e.g., 41,42).…”

Section: Symbiosis As a Route To Adaptation And Complexity In Eukaryotesmentioning

confidence: 99%

Symbiosis as an adaptive process and source of phenotypic complexity

Moran

2007

Proc. Natl. Acad. Sci. U.S.A.

440

361

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Genomics has revealed that inheritance systems of separate species are often not well segregated: genes and capabilities that evolve in one lineage are often stably acquired by another lineage. Although direct gene transfer between species has occurred at some level in all major groups, it appears to be far more frequent in prokaryotes than in multicellular eukaryotes. An alternative to incorporating novel genes into a recipient genome is acquiring a stable, possibly heritable, symbiotic association and thus enjoying benefits of complementary metabolic capabilities. These kinds of symbioses have arisen frequently in animals; for example, many insect groups have diversified on the basis of symbiotic associations acquired early in their evolutionary histories. The resulting associations are highly complex, often involving specialized cell types and organs, developmental mechanisms that ensure transfer of symbionts between generations, and mechanisms for controlling symbiont proliferation and location. The genomes of longterm obligate symbionts often undergo irreversible gene loss and deterioration even as hosts evolve dependence on them. In some cases, animal genomes may have acquired genes from symbionts, mirroring the gene uptake from mitochondrial and plastid genomes. Multiple symbionts often coexist in the same host, resulting in coadaptation among several phylogenetically distant genomes.

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Section: Symbiosis As a Route To Adaptation And Complexity In Eukaryotesmentioning

confidence: 99%

Symbiosis as an adaptive process and source of phenotypic complexity

Moran

2007

Proc. Natl. Acad. Sci. U.S.A.

440

361

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“…The family of proteins is highly conserved (around 55%) between species as far removed as yeast and humans (Chen et al 2006). HSP-90 is known not only for responding to heat stress, but also is used as a housekeeping protein, chaperoning proteins to ensure that they fold properly.…”

Section: Fungus-conferred Heat Tolerance In Desert Plantsmentioning

confidence: 99%

“…HSP-90 comprises 1-2% of all proteins in the cytosol of unstressed cells (Chen et al 2006), and up to 4 -6% of heat-stressed cells (Crevel et al 2001). …”

Section: Fungus-conferred Heat Tolerance In Desert Plantsmentioning

confidence: 99%

Symbiosis as a source of selectable epigenetic variation: taking the heat for the big guy

Gilbert

McDonald

Boyle

et al. 2010

Phil. Trans. R. Soc. B

129

110

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Evolutionary developmental biology is based on the principle that evolution arises from hereditable changes in development. Most of this new work has centred on changes in the regulatory components of the genome. However, recent studies (many of them documented in this volume) have shown that development also includes interactions between the organism and its environment. One area of interest concerns the importance of symbionts for the production of the normal range of phenotypes. Many, if not most, organisms have 'outsourced' some of their developmental signals to a set of symbionts that are expected to be acquired during development. Such intimate interactions between species are referred to as codevelopment, the production of a new individual through the coordinated interactions of several genotypically different species. Within the past 2 years, several research programmes have demonstrated that such codevelopmental schemes can be selected. We will focus on symbioses in coral reef cnidarians symbiosis, pea aphids and cactuses, wherein the symbiotic system provides thermotolerance for the composite organism.

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“…They also play key roles in the maturation of signal transduction proteins, such as hormone receptors, protein kinases, and nitric oxide synthase, by forming specific complexes (Csermely et al 1998;Garcia-Cardena et al 1998;Imai and Yahara 2000;Richter and Buchner 2001). Although more than 100 genes belonging to the HSP90 family exist in various organisms (Chen et al 2006), little is known about HSP90 genes in mollusks (Tomanek and Somero 1999;Ochoa et al 2002;Farcy et al 2007;Gao et al 2007). To the best of our knowledge, full-length complementary DNA (cDNA) sequences of HSP90s have been cloned from only five mollusk species, Haliotis tuberculata, H. asinina, Chlamys farreri, Crassostrea gigas, and Argopecten irradians (Farcy et al 2007;Gao et al 2007Gao et al , 2008Gunter and Degnan 2007;Choi et al 2008).…”

Section: Introductionmentioning

confidence: 99%

Molecular characterization and induction of heat shock protein 90 in the Antarctic bivalve Laternula elliptica

Kim

Ahn

Kim

et al. 2009

Cell Stress and Chaperones

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Heat shock protein 90 (HSP90) is a highly conserved molecular chaperone that plays a key role in protein synthesis, folding, denaturation prevention, and signal transduction. We cloned the complete complementary DNA (cDNA) sequence of the Laternula elliptica HSP90. The full-length cDNA was 2,823 bp in size and contained an open reading frame of 2,190 bp that was translated into 729 amino acids with a calculated molecular weight of 83.4 kDa. The deduced amino acid sequence of HSP90 showed the highest homology to Haliotis tuberculata HSP90 (83%). Reverse-transcriptase polymerase chain reaction analysis revealed the presence of HSP90 transcripts in all of the tissues examined. We also studied the transcriptional expression pattern of HSP90 exposed to thermal stress with real-time polymerase chain reaction. The relative expression level of HSP90 messenger RNA was upregulated and peaked at 12 h in the digestive gland and at 24 h in the gills, then dropped progressively.

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Comparative genomics and evolution of the HSP90 family of genes across all kingdoms of organisms

Cited by 286 publications

References 68 publications

Symbiosis as an adaptive process and source of phenotypic complexity

Symbiosis as an adaptive process and source of phenotypic complexity

Symbiosis as a source of selectable epigenetic variation: taking the heat for the big guy

Molecular characterization and induction of heat shock protein 90 in the Antarctic bivalve Laternula elliptica

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