Comparative investigations of the desensitising efficacy of a new dentifrice

Abstract

These studies demonstrate that the new dentifrice, containing potassium nitrate, stannous fluoride and sodium fluoride is significantly better at reducing dentine hypersensitivity than both the dentifrice containing sodium fluoride and the one containing potassium chloride, triclosan and sodium fluoride (Sensodyne F).

The Efficacy of Strontium and Potassium Toothpastes in Treating Dentine Hypersensitivity: A Systematic Review

“…In summary, 32 strontium-related studies were excluded (Table 1) and only 1 study was included in the present paper (Table 3). The reasons for the exclusion of the 55 potassium-based toothpaste studies were mainly due to the different fluoride concentrations and/or ingredient(s) in the test and comparison toothpastes [49, 50, 54, 56, 68, 79, 82, 88, 97] (Table 2). For example, three studies were excluded since the main aim of these studies was to evaluate the efficacy of KNO 3 toothpaste/gel in reducing bleaching sensitivity during or following tooth whitening/bleaching procedures [52, 62, 63].…”

A clinical study of the effect of calcium sodium phosphosilicate on dentin hypersensitivity

“…Potassium nitrate containing dentifrices have consistently shown benefit in alleviating the hypersensitivity symptoms (5-7). They mainly act by blocking the neural transmission.…”

Clinician's Guide to the Diagnosis and Management of Tooth Sensitivity

“…Treatment may be delivered in a stratifi ed manner, as indicated in Fig. A similar picture emerges when evaluating potassium-containing toothpastes despite the vast numbers of published studies (Tarbet et al 1980(Tarbet et al , 1981Silverman 1985 ;Silverman et al 1994 ;Nagata et al 1994 ;Salvato et al 1992 ;Schiff et al 1994Schiff et al , 1998Schiff et al , 2000Sowinski et al 2000Sowinski et al , 2001Waraaswapati et al 2005 ;Yates et al 2005 ), and a number of investigators have raised concerns with regard to the effi cacy of potassium-containing toothpastes which has led to the suggestion that potassium-containing toothpastes may be no more effective than regular fl uoride toothpaste (Gillam et al 1996a ;Jackson 2000 ;Cummings 2009 ). With localised or severe DH, practitioners may prefer to treat the patient directly, using an in-offi ce procedure Note 4.…”

“…classifi ed these in-offi ce treatment modalities on the basis of (1) whether they do not polymerise (varnishes/precipitants/ primers containing HEMA), (2) whether they undergo setting or polymerisation reactions (conventional glass ionomer cements, or resinreinforced glass ionomers/compomers; adhesive resin primers; adhesive resin bonding systems), (3) the use of mouthguards, (4) iontophoresis and (5) lasers. For example, the treatment of post-operative sensitivity may involve the application of a desensitiser underneath a crown or restoration (Haywood 2002 ;Jalandar et al 2012 ) as well as post-operative sensitivity following periodontal therapy , Pashley et al ( 2008 ) modifi ed Table 6.3 Summary of the published studies supporting the effi cacy of in-offi ce products (adhesives, resins and cements) Gangarosa and Park ( 1978 ), Brough et al ( 1985 ), Gupta Tarbet et al ( 1980Tarbet et al ( , 1981, Silverman ( 1985 ) Silverman et al ( 1996Silverman et al ( , 1994, Nagata et al ( 1994 ), Salvato et al ( 1992 ), Schiff et al ( 1994Schiff et al ( , 1998Schiff et al ( , 2000, Sowinski et al ( 2000Sowinski et al ( , 2001, Waraaswapati et al ( 2005 ) International) prior to the provision of an OTC desensitising toothpaste for home use (Hamlin et al 2009 ;Schiff et al 2009 ;Milleman et al 2012 ;. Generally speaking in-offi ce treatment modalities involve patients who complain of DH localised to one or two teeth with moderate to severe discomfort and as such would require immediate attention.…”