Comparative &lt;i&gt;In vitro&lt;/i&gt; Anthelmintic Activity of &lt;i&gt;Mentha piperita&lt;/i&gt; and &lt;i&gt;Lantana camara&lt;/i&gt; from Western India

Girme, Aboli; Bhalke, R. D.; Ghogare, PB; Tambe, VD; Jadhav, R. S.; Nirmal, S. A.

doi:10.3329/dujps.v5i1.220

Cited by 20 publications

(14 citation statements)

References 14 publications

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“…Three worms of nearly the same size per dose were used. Time for paralysis in minutes was noted when no movement of any sort could be observed, except when the worm was shaken vigorously, while the time of death in minutes was recorded after ascertaining the worms neither moved when shaken vigorously nor when they were dipped in warm water (50°C) (Ajaiyeoba et al 2001;Girme et al 2006) and followed by fading away of their body colours. Piperazine hydrate (PC; 10 mg/ml) was used as the reference drug (Ajaiyeoba et al 2001;Mali et al 2004).…”

Section: Evaluation Of Anthelmintic Activitymentioning

confidence: 99%

Anthelmintic activities of chloroform and methanol extracts of Buchholzia coriacea Engler seed

2011

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The anthelmintic potentials of the chloroform and methanol extracts of Buchholzia coriacea Engler seed were investigated. In folklore medicine, B. coriacea (Capparidaceae) is believed to be useful in the treatment of various kinds of ailments and diseases. At doses of 10 mg/kg, 25 mg/kg and 50 mg/kg, the extracts were tested against Eudrilus eugeniae (earthworm) and Bunostomum phlebotomum (cattle hookworm). The extracts exhibited dose-dependent anthelmintic effects on the earthworms and hookworms. The methanol extract at 50 mg/kg was the most active extract against the helminths, and the activity of the methanol extract was not significantly different from that of piperazine hydrate (reference drug, 10 mg/kg) against the earthworms.

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Section: Evaluation Of Anthelmintic Activitymentioning

confidence: 99%

Anthelmintic activities of chloroform and methanol extracts of Buchholzia coriacea Engler seed

2011

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“…Paralysis was said to occur when the worms were not able to move even in normal saline. Death was concluded when the worms lost their motility followed with fading away of their body colors 20 . Death was also confirmed by dipping the worms in slightly warm water.…”

Section: Anthelmintic Activity Of Solvent Extractmentioning

confidence: 99%

Evaluation of Anthelmintic Activity of Lichen Usnea Undulata Stirt. (Parmeliaceae)

Kanivebagilu¹,

Mesta²

2016

Int. J. Res. Ayurveda Pharm.

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Lichen compounds are also known to have biological activities. Traditionally Usnea used as antibacterial, antidermatophytic and anthelmintic. The present study was carried to determine the anthelmintic activity of a macrolichen Usnea undulata Stirt. (Parmeliaceae) collected from forest area of Chikmagalur district. The lichen was powdered and extracted sequentially using solvents of increasing polarity viz., acetone, methanol and water. Thin layer chromatography showed the presence of usnic acid. The anthelmintic assay was performed on Pheretima pasthuma. High inhibitory potential was observed in case of acetone extract. Inhibitory effect could be ascribed to the bioactive secondary metabolites, mainly Usnic acid present in the lichen. Purification of bioactive principles is to be conducted.

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“…Time for paralysis was noted when no movement of any sort could be observed except when the worms were shaken vigorously. Death was concluded when the worms lost their motility followed with fading away of their body colors (Grime et al, 2006). Death was also confirmed by dipping the worms in slightly warm water.…”

Section: In-vitro Anthelmintic Assaymentioning

confidence: 99%

Study of antidiarrheal and anthelmintic activity methanol extract of Commelina benghalensis leaves

Kabir¹,

Hasanat²,

Tanvir³

et al. 2016

Afr. J. Pharm. Pharmacol.

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The objective of this study was to examine the restorative effects of methanol extract of Commelina benghalensis leaves in antidiarrheal activity in Swiss albino mice model and anthelmintic activity in Tubifex tubifex. Antidiarrheal activity study in Swiss albino mice were divided into four groups. Group I was treated as the control group and received 10 ml/kg of 2% Tween-80 orally; Group II served as a positive control and took standard drug (loperamide) in 5 mg/kg orally; Groups III and IV were the test groups which received the methanol extract of C. benghalensis orally at 200 and 400 mg/kg, respectively. Dependent upon the model comprehensive weight of dry feces, aggregate weight of wet defecation, length of intestinal travel and intestinal weight were gathered. At long last, information were investigated using restricted analysis of variance (ANOVA) took after by Dunnett test. Anthelmintic action on aquarium worm T. tubifex by utilizing three focuses of 10, 5, and 2.5 mg/ml of C. benghalensis movement was assessed by in vitro system. The property of the extract on defecation, intestinal transit and intestinal fluid accumulation (antienteropooling) were assessed in castor oil induced diarrhea. Leaves extract of C. benghalensis at 200 and 400 mg/kg exhibited significant (p<0.05, 0.01 and 0.001) and dose dependent antidiarrheal probable in castor oil induced diarrhea. The diarrhea was inhibited by 27.59 and 55.17 at doses of 200 and 400 mg/kg in that order. The extract were found to have an antienteropooling in castor oil affected test Swiss albino mice's by decreasing both weight and volume of intestinal substance, and obviously reducing the intestinal travel similar to that of the standard medication, loperamide (5 mg/kg). Anthelmintic activity of methanol extract C. benghalensis show the time taken for paralysis (12.38, 16.25 and 22.17 min) and time taken for death (21.39, 45.64 and 57.25 min) at doses of 10, 5, and 2.5, respectively. The methanol extract of C. benghalensis demonstrated antidiarrheal effect in Swiss albino mice model and anthelmintic action on aquarium worm T. tubifex. In addition, the extract was discovered to be safe at measurements of 1000, 2000, 3000, and 4000 mg/kg in mice model. The discoveries propose the legitimacy of the much lauded impact of C. benghalensis as antidiarrheal and anthelmintic specialists in expected home grown medication.

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Comparative <i>In vitro</i> Anthelmintic Activity of <i>Mentha piperita</i> and <i>Lantana camara</i> from Western India

Cited by 20 publications

References 14 publications

Anthelmintic activities of chloroform and methanol extracts of Buchholzia coriacea Engler seed

Anthelmintic activities of chloroform and methanol extracts of Buchholzia coriacea Engler seed

Evaluation of Anthelmintic Activity of Lichen Usnea Undulata Stirt. (Parmeliaceae)

Study of antidiarrheal and anthelmintic activity methanol extract of Commelina benghalensis leaves

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