1993
DOI: 10.1097/00006676-199309000-00003
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Comparative Study of Antibacterial Activity of Pancreatic Juice in Six Mammalian Species

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Cited by 20 publications
(9 citation statements)
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“…The production of hBD-I by various sites within the female genitourinary tract [16] will be described elsewhere. The prominent expression of hBD-1 in the pancreas might be related to protecting pancreatic ductal and acinar epithelial cells from retrograde infection via the pancreatic duct, or might contribute to the antimicrobial properties of pancreatic secretions [17], thereby compensating for the low density of c~-defensin producing Paneth cells in the duodenum [18].…”
Section: Resultsmentioning
confidence: 99%
“…The production of hBD-I by various sites within the female genitourinary tract [16] will be described elsewhere. The prominent expression of hBD-1 in the pancreas might be related to protecting pancreatic ductal and acinar epithelial cells from retrograde infection via the pancreatic duct, or might contribute to the antimicrobial properties of pancreatic secretions [17], thereby compensating for the low density of c~-defensin producing Paneth cells in the duodenum [18].…”
Section: Resultsmentioning
confidence: 99%
“…The lack of pancreatic enzymes and thus inadequate digestion of the food results in a decreased nutrient utilization and thus excess of nutrients in the gut lumen, eventually leading to bacterial overgrowth, as has been observed in several species [2,4,5]. Furthermore, the lack of pancreatic juice and its content of antimicrobial components as shown in pigs and other species might affect the microflora [6][7][8].…”
Section: Introductionmentioning
confidence: 99%
“…These potent peptides in their tissues could be related to the fact that their exposure to contaminated food is much higher than other birds . Various body fluids such as pancreatic juice which is present in intestine of mammals including rabbit, guinea pig, pig, sheep and cattle were found to possess antibacterial activities against Micrococcus pyogenes . Similarly, antimicrobial peptides which are also present in different body tissues and secretions of mammals are meant to exhibit potent antimicrobial activities against broad range of microorganisms .…”
Section: Animal‐based Antimicrobial Discovery: a Largely Untapped Soumentioning
confidence: 99%
“…[118] Various body fluids such as pancreatic juice which is present in intestine of mammals including rabbit, guinea pig, pig, sheep and cattle were found to possess antibacterial activities against Micrococcus pyogenes. [120] Similarly, antimicrobial peptides which are also present in different body tissues and secretions of mammals are meant to exhibit potent antimicrobial activities against broad range of microorganisms. [121] AMPs have diverse amino acid sequences and structures, but most are small amphipathic, cationic peptides.…”
Section: Secretions Of Mammalian Myeloid and Epithelial Cellsmentioning
confidence: 99%