Comparative Study of Caudal Ropivacaine and Ropivacaine - Clonidine Combination in Paediatric Urogenital Surgeries for Post - Operative Analgesia

Berde, Ravi; Nema, Neelesh; Minj, Bhuvneswar; Mujalde, Mahendra; Nandkishore, Nandkishore; Amit, Amit; Nidhi, Nidhi

doi:10.14260/jemds/2015/1510

Cited by 3 publications

(1 citation statement)

References 7 publications

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“…Paracetamol was given orally for cases with FLACC score 4 or more. 7 Our study is well compared with the above study. In our study the efficacy of caudal epidural clonidine 1 µg/kg with 0.75 ml/kg ropivacaine 0.2% in prolonging post-operative analgesia between Group (ropivacaine with clonidine) and Group (ropivacaine) were statically significant at various points.…”

Section: Discussionsupporting

confidence: 57%

Comparison of Post-Operative Analgesia after Single Shot Caudal Epidural Block Using Ropivacaine with or without Clonidine in Children

Pore¹

2019

jmscr

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Caudal epidural block is one of the most common regional anesthetic techniques in children being used to supplement general anesthesia for a wide variety of surgeries. The local anesthetics currently in use are safe and their pharmacological effects have been well evaluated. The aim of this study is to clinically evaluate the efficacy of caudal epidural clonidine in prolonging the post-operative analgesia when mixed with ropivacaine in children and to compare the post-operative pain-free duration and the side effects of ropivacaine with or without Clonidine. The addition of α-2 agonist, Clonidine to local anesthetic solution 0.2% ropivacaine has been shown to enhance the duration and quality of central and peripheral nerve blocks. The main advantage of Clonidine (versus opioids) is the negligible risk of respiratory depression.

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Section: Discussionsupporting

confidence: 57%

Comparison of Post-Operative Analgesia after Single Shot Caudal Epidural Block Using Ropivacaine with or without Clonidine in Children

Pore¹

2019

jmscr

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Comparison of adjuvant pharmaceuticals for caudal block in pediatric lower abdominal and urological surgeries: A network meta-analysis

Xiong¹,

Han²,

Lv³

et al. 2022

Journal of Clinical Anesthesia

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A Comparative Evaluation of Ropivacaine Hydrochloride and Ropivacaine Hydrochloride With Dexmedetomidine for Caudal Epidural Anaesthesia in Paediatric Patients Undergoing Elective Infraumbilical Surgeries

Goyal¹,

Yadav²,

Ranjan³

et al. 2017

jemds

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BACKGROUND The aim of this study is to compare the efficacy of ropivacaine hydrochloride and ropivacaine hydrochloride with dexmedetomidine in caudal epidural anaesthesia for postoperative pain relief in paediatric patients undergoing elective infraumbilical surgeries. MATERIALS AND METHODS A prospective randomised study was carried out, which included sixty paediatric patients between the ages of 2-8 years of ASA Grade I/II patients who underwent infraumbilical surgeries. Patients were randomly divided into two Groups R and RD of thirty patients each. Group R received ropivacaine 0.2% 1 mL/kg with 0.5 mL normal saline, while Group RD received ropivacaine 0.2% 1 mL/kg with dexmedetomidine 2 mcg/kg diluted to 0.5 mL of normal saline. Duration of analgesia, duration of motor blockade, sedation and side effects were observed. The data obtained was subjected to statistical computation with analysis of variance and chi-square test using Statistical Package for Sciences (SPSS) version 10 for windows and value of P < 0.05 was considered significant and P < 0.001 as highly significant. RESULTS The demographic profile, intra-and post-operative block characteristics and cardiorespiratory parameters were comparable and non-significant in both the groups. However, duration of postoperative analgesia is significantly prolonged in RD group as compared to R group. Sedation score with dexmedetomidine were better and turned out to be statistically significant. Side effect profile was also comparable. CONCLUSION Dexmedetomidine is a better neuraxial adjuvant for providing adequate sedation and prolonged post-operative analgesia.

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Comparative Study of Caudal Ropivacaine and Ropivacaine - Clonidine Combination in Paediatric Urogenital Surgeries for Post - Operative Analgesia

Cited by 3 publications

References 7 publications

Comparison of Post-Operative Analgesia after Single Shot Caudal Epidural Block Using Ropivacaine with or without Clonidine in Children

Comparison of Post-Operative Analgesia after Single Shot Caudal Epidural Block Using Ropivacaine with or without Clonidine in Children

Comparison of adjuvant pharmaceuticals for caudal block in pediatric lower abdominal and urological surgeries: A network meta-analysis

A Comparative Evaluation of Ropivacaine Hydrochloride and Ropivacaine Hydrochloride With Dexmedetomidine for Caudal Epidural Anaesthesia in Paediatric Patients Undergoing Elective Infraumbilical Surgeries

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