Comparative study of different laser systems

Bhatta, Nayantara; Isaacson, Keith; Bhatta, Krishna M.; Anderson, R. Rox; Schiff, Isaac

doi:10.1016/s0015-0282(16)56629-1

Cited by 35 publications

(27 citation statements)

References 35 publications

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“…Neodynium:yttrium-aluminumgarnet (Nd:YAG) lasers have short wavelengths (1064 nm and 1440 nm) within the infrared (invisible) zone of the spectrum. Neodynium's wavelength is relatively poorly absorbed by water (and thus most relevant to musculoskeletal tissues), and it therefore penetrates tissue for relatively greaterthan-desired depths, estimated at 4-6 mm in a vascular tissue [1,2]. When less is absorbed by target tissue, more laser energy is transmitted beyond the target.…”

Section: Properties Of Laser Lightmentioning

confidence: 99%

“…This unintended effect can lead to inadvertent heating of deeper tissues and clinically significant thermal damage. Reports of thermal necrosis caused by subchondral bone penetration soon followed the clinical introduction of the Nd:YAG laser and signified its rapid efficiency demise [1,2].…”

Section: Properties Of Laser Lightmentioning

confidence: 99%

“…Diode lasers generate low powers generally below 1.0 W. The diode laser is an example of a semiconductor laser used in ophthalmology for photocoagulation. Fibers easily transmit diode laser radiation, which can be pulsed or continuous [2].…”

Section: Laser Chemistrymentioning

confidence: 99%

“…HeNe lasers only operate in continuous-wave (CW) mode and no cooling system is required. The maximum power output (50-60 mW) is so weak that these are not useful as surgical lasers [2,3]. The laser can be used as a visible guide beam that accompanies otherwise invisible treating laser beams.…”

Section: Laser Chemistrymentioning

confidence: 99%

“…A penetration depth of even some microns can be regarded as sufficient, because most of the relevant target cells of low-level laser irradiation, namely fibroblasts, keratinocytes, macrophages, and endothelial cells for the induction of wound healing, are located within the epidermis and upper dermis [4]. The HeNe laser has been reported to stimulate wound healing and cell growth [4] and is frequently used for biostimulation in pain management and for wound healing [2].…”

Section: Laser Chemistrymentioning

confidence: 99%

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Changes in Cell Viability of Wounded Fibroblasts following Laser Irradiation in Broad‐Spectrum or Infrared Light

Hawkins

Abrahamse

2006

Laser Chemistry

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Objective. This study aimed to establish if broad-spectrum or infrared (IR) light in combination with laser therapy can assist phototherapy to improve the cell function of wounded cells. Background. The effect of laser light may be partly or completely reduced by broad-spectrum light. Methods. Wounded human skin fibroblasts were irradiated with 5 J/cm 2 using a helium-neon laser, a diode laser, or an Nd:YAG laser in the dark, in the light, or in IR. Changes in cell viability were evaluated by cell morphology, ATP cell viability, LDH membrane integrity, and caspase 3/7 as an early marker of apoptosis. Results. Wounded cells exposed to 5 J/cm 2 using 632.8 nm in the dark or 830 nm in the light or 1064 nm in the dark showed an increase in ATP viability, an increase in cytokine expression, and a decrease in LDH cytotoxicity indicating that the metabolic activity of the wounded cells was stimulated. Conclusion. Wounded cells irradiated in IR light showed an undesirable thermal effect that was proportional to the duration of exposure.

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Section: Properties Of Laser Lightmentioning

confidence: 99%

Section: Properties Of Laser Lightmentioning

confidence: 99%

Section: Laser Chemistrymentioning

confidence: 99%

Section: Laser Chemistrymentioning

confidence: 99%

Section: Laser Chemistrymentioning

confidence: 99%

See 3 more Smart Citations

Changes in Cell Viability of Wounded Fibroblasts following Laser Irradiation in Broad‐Spectrum or Infrared Light

Hawkins

Abrahamse

2006

Laser Chemistry

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Clinical and preclinical photodynamic therapy

1995

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Photodynamic therapy (PDT) is a treatment modality that utilizes a photosensitizing drug activated by laser generated light, and is proving effective for oncologic and nononcologic applications. This report provides an overview of photosensitizers, photochemistry, photobiology, and the lasers involved in photodynamic therapy. Clinical and preclinical PDT studies involving Photofrin and various second generation photosensitizers are reviewed.

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NIR laser tissue welding of in vitro porcine cornea and sclera tissue

et al. 2004

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We conclude that an NIR laser system using an optimal laser radiation wavelength of 1,455 nm can effectively weld cornea and sclera tissue and that this laser tissue welding (LTW) methodology typically causes minimal disruption of tissue, and thus, avoids opacities and irregularities in the tissue which may result in decreased visual acuity. The optimization of a laser welding system that leads to a strong full thickness tissue bond without tissue destruction, an instant seal that promotes wound healing, and the absence of a continued presence of a foreign substance like a suture, is of considerable importance to the ophthalmology medical community. This need is especially apparent with respect to corneal transplantation and fixing the position of corneal flaps in Laser-Assisted In Situ Keratomileusis (LASIK), a laser procedure used to permanently change the shape of the cornea.

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Comparative study of different laser systems

Cited by 35 publications

References 35 publications

Changes in Cell Viability of Wounded Fibroblasts following Laser Irradiation in Broad‐Spectrum or Infrared Light

Changes in Cell Viability of Wounded Fibroblasts following Laser Irradiation in Broad‐Spectrum or Infrared Light

Clinical and preclinical photodynamic therapy

NIR laser tissue welding of in vitro porcine cornea and sclera tissue

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