Comparative study of human papilloma virus in untreated and ultraviolet-treated psoriatic patients

Salem, Samar Abdallah Mohamed; Zuel-Fakkar, Nehal Mohamed; Fathi, Ghada; El-Reheem, Sameh Mostafa Abd; El-Tabakh, Alaa Abd El-monem; Ragab, Dalia

doi:10.1111/j.1600-0781.2010.00492.x

Cited by 7 publications

(9 citation statements)

References 13 publications

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“…Salem and colleagues demonstrated recovery of more HPV in psoriatic plaques treated with UVB and psoralen plus UVA (PUVA) than in nonirradiated psoriatic plaques and normal controls. 45 That same study found that there was an even greater recovery in PUVA-treated patients with psoriasis than in those treated with narrowband UVB (NB-UVB), suggesting that the UV wavelength and degree of damage is important in HPV infection. Furthermore, when the authors examined UV-treated patients with vitiligo, they found that HPV recovery in lesional skin in these patients was similar to that in the psoriasis-PUVA group but significantly higher than in the psoriasis-NB-UVB group.…”

Section: Ultraviolet Light and Hpvmentioning

confidence: 96%

“…The destructive effects of UV light may also play a role in HPV infection. Salem and colleagues demonstrated recovery of more HPV in psoriatic plaques treated with UVB and psoralen plus UVA (PUVA) than in nonirradiated psoriatic plaques and normal controls . That same study found that there was an even greater recovery in PUVA‐treated patients with psoriasis than in those treated with narrowband UVB (NB‐UVB), suggesting that the UV wavelength and degree of damage is important in HPV infection.…”

Section: Ultraviolet Light and Hpvmentioning

confidence: 98%

“…Persistent infection with a high-risk a HPV type is necessary, although not sufficient, for the development of cervical cancer, 12 and almost all cervical cancers test positive for HPV DNA. 12 Infection with high-risk HPVs (16,18,31,33,45), whether clinically evident or not, is the major risk factor for the development of cervical cancer. 13 In addition, the attributable risk of HPV for cervical cancer is higher than the risk associated with smoking for lung cancer and hepatitis B for liver cancer.…”

mentioning

confidence: 99%

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Cutaneous Squamous Cell Carcinoma and Human Papillomavirus: Is There an Association?

Aldabagh

Angeles

Cardones

et al. 2013

Dermatologic Surgery

100

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Background The role of human papillomavirus (HPV) in the induction and maintenance of cervical, anogenital, and some oropharyngeal carcinomas is well recognized. However, its role in cutaneous squamous cell carcinoma (SCC) remains to be elucidated. HPV is thought to act as a possible co-carcinogen in the development of SCC. Objective To review the literature assessing the correlation and possible causation of HPV and cutaneous SCC in the immunocompetent and immunocompromised populations. Methods We reviewed HPV sampling and detection methods, epidemiologic studies examining HPV carriage in immunocompetent and immunosuppressed individuals, and evidence asserting an association between HPV and cutaneous SCC. Results Although an abundant body of evidence points toward a link between HPV and cutaneous SCC, many studies indicate otherwise. Recent studies have focused on viral activity in addition to DNA presence. Conclusion The possibility exists that HPV may play a role in the induction but not maintenance of cutaneous SCC.

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Section: Ultraviolet Light and Hpvmentioning

confidence: 96%

Section: Ultraviolet Light and Hpvmentioning

confidence: 98%

mentioning

confidence: 99%

See 1 more Smart Citation

Cutaneous Squamous Cell Carcinoma and Human Papillomavirus: Is There an Association?

Aldabagh

Angeles

Cardones

et al. 2013

Dermatologic Surgery

100

View full text Add to dashboard Cite

show abstract

“…This difference is likely to reflect the facts that non-scar SCC is more common in countries with predominantly light-skinned populations and that UV-induced SCC is relatively less common in countries with dark-skinned individuals. 33 Immunocompromised individuals have a high risk for acquiring HPV and subsequent malignant transforma-tion because the adaptive immune system (functional T cell response) is integral to fighting HPV infection. 4).…”

Section: Pathogenesismentioning

confidence: 99%

Squamous cell carcinoma of the skin: epidemiology, classification, management, and novel trends

2014

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Squamous cell carcinoma (SCC) is the second most common non-melanoma skin cancer. It originates from epidermal keratinocytes or adnexal structures (such as eccrine glands or pilosebaceous units). We describe the salient features of cutaneous SCC. We also review novel classification schemes proposed during the last decade which attempt to stratify SCC lesions based on prognosis. Biopsy leads to definitive diagnosis. Treatment includes surgical excision; Mohs micrographic surgery produces excellent cure rates and spares the maximal amount of tissue. Other modalities include electrodessication and curettage, cryosurgery, radiotherapy, topical medications, photodynamic therapy, and systemic therapy. Management and follow-up depend on the risk stratification of individual lesions.

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“…The hypothesis was to verify whether there was a relation between the clinical evolution of the disease and the presence of HPV as an aggravating factor (9,15).…”

Section: Discussionmentioning

confidence: 99%

Ulerythema Ophryogenes, a Rare and Often Misdiagnosed Syndrome: Analysis of an Idiopathic Case

Dianzani

Pizzuti

Gaspardini

et al. 2011

Int J Immunopathol Pharmacol

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Keratosis pilaris (KP) is a follicular hyperkeratosis disorder which is frequently detected in the adult population (44%), mostly in female adolescents (80%). It is a genetic autodominant dermatosis with variable penetrance, but no specific gene association has been determined, even though association to the presence of chromosome 18p deletion has been reported in some cases. We report the case of a 51-year-old Caucasian woman affected by keratosis pilaris gradually progressing with age and with a story of multiple abortions. Standard karyotype and CGH array analyses did not reveale any genetic abnormality. Virological analyses detected the presence of HPV 36 DNA inside the dorsum biopsy, leading to hypothesize its involvement in the evolution of the lesion. Clinical history and patient examination led the diagnosis of an idiopathic case of Ulerythema ophryogenes. The analysis of more cases could be useful to verify the involvement of cutaneous HPV in the progression of the clinical manifestation of the KP variants.

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Comparative study of human papilloma virus in untreated and ultraviolet-treated psoriatic patients

Abstract: UV treatment may be an underlying factor predisposing patients with psoriasis to infectivity by HPV together with other factors.

Cited by 7 publications

References 13 publications

Cutaneous Squamous Cell Carcinoma and Human Papillomavirus: Is There an Association?

Cutaneous Squamous Cell Carcinoma and Human Papillomavirus: Is There an Association?

Squamous cell carcinoma of the skin: epidemiology, classification, management, and novel trends

Ulerythema Ophryogenes, a Rare and Often Misdiagnosed Syndrome: Analysis of an Idiopathic Case

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