Comparative study of mannose-binding C-type lectin isolated from channel catfish (Ictalurus punctatus) and blue catfish (Ictalurus furcatus)

Molecular profiling of the gilthead sea bream (Sparus aurata L.) response to chronic exposure to the myxosporean parasite Enteromyxum leei

“…MBL levels contribute to the severity of illness in several bacterial infections (Hibberd et al, 1999;Roy et al, 2002;Kars et al, 2005) and low MBL levels are associated with increased risk, severity and frequency of some infections (Botto et al, 2009). In fish species MBL have been reported in trout, salmon, carp, rohu fish, channel catfish, blue 16 catfish and sea lamprey (Jensen et al, 1997;Ewart et al, 1999;Vitved et al, 2000;Mitra and Das, 2002;Ourth et al, 2007Ourth et al, , 2008 and functional binding studies to fish pathogens have suggested a similar lectin complement pathway for these species (Ewart et al, 1999;Ourth et al, 2007Ourth et al, , 2008. Analysis by qPCR confirmed the down-regulated expression pattern of MBL2 in the INT of R-PAR fish (148-fold) whereas in R-NonPAR fish down-regulation was less apparent (1.7-fold).…”

“…Analysis by qPCR confirmed the down-regulated expression pattern of MBL2 in the INT of R-PAR fish (148-fold) whereas in R-NonPAR fish down-regulation was less apparent (1.7-fold). Ourth et al (2007) have suggested that MBL could be used as a genetic marker for disease resistance in the different strains of cultured catfish, as those more resistant to Edwardsiella ictaluri had nearly three fold higher levels of serum MBL. In other infection studies the transcriptomic responses of MBL were dependent on the pathogen involved, as demonstrated by the 4.2-fold down-regulation of the MBL gene in the gills of AGD-affected Atlantic salmon (Morrison et al, 2006), and the 2-fold up-regulation in juvenile Atlantic salmon infected with saprolegniasis, a fungal infection (Roberge et al, 2007).…”

Physiology and immunology of mucosal barriers in catfish (Ictalurus spp.)

“…[68][69][70] MBLs are important for induction of the complement system via mannose-binding lectin-associated serine proteases (MASPs). MBLs have been identified in the proteome of skin mucus from Atlantic cod, indicating they may be present constitutively at barrier defenses.…”

Innate immune response of channel catfish Ictalurus punctatus mannose-binding lectin to channel catfish virus (CCV)

“…CCV generally infects catfish less than 6 mo old, and epizootics can result in 95% losses of catfish fry and fingerlings in pond aquaculture (Fijan et al 1970, Plumb 1978, Thune 1993, Stingley & Gray 2000. Channel catfish mannose-binding lectin (MBL) and blue catfish MBL can bind to Edwardsiella ictaluri (Ourth et al 2007), a Gramnegative bacterium that causes enteric septicemia of catfish. However, the binding ability of blue catfish MBL to E. ictaluri was greater than that of channel catfish.…”