“Comparative Study of Platelet Rich Plasma Versus Autologous Temporalis Fascia Graft in Type 1 Tympanoplasty.”

Abstract

Background: Chronic otitis media (COM) is most common disease seen by ENT surgeon. Tympanoplasty using temporalis fascia as graft is routine treatment procedure while Platelet Rich Plasma (PRP)is newer treatment procedure. Methods: Prospective Study conducted on participants admitted with Chronic otitis media in the Otorhinolaryngology department of Sri Siddhartha Medical College hospital and Research Centre, Tumkur from December 2020 to June 2022 which includes 60 participants and were divided into two groups PRP group (30 participants) where PRP used as graft material and T group (30 participants) where temporalis fascia was used as graft material and follow up done at 3rd month and 6th month for assessing closure of perforation and for hearing improvement using pure tone audiometry. Results: Among 30 cases of PRP group, there were 29 cases of closure of perforation (96.67 %) and 1 case had no closure of perforation (3.33 %). Among 30 cases of T group, there were 28 cases of closure of perforation (93.33%) and 2 cases had no closure of perforation (6.67%). The p-value calculated between the groups with pre operative mean air bone gap values was 0.2210 and that with post operative values was 0.1835; indicating no signicant difference between the groups during follow up at 6 months.Background: Chronic otitis media (COM) is most common disease seen by ENT surgeon. Tympanoplasty using temporalis fascia as graft is routine treatment procedure while Platelet Rich Plasma (PRP)is newer treatment procedure. Methods: Prospective Study conducted on participants admitted with Chronic otitis media in the Otorhinolaryngology department of Sri Siddhartha Medical College hospital and Research Centre, Tumkur from December 2020 to June 2022 which includes 60 participants and were divided into two groups PRP group (30 participants) where PRP used as graft material and T group (30 participants) where temporalis fascia was used as graft material and follow up done at 3rd month and 6th month for assessing closure of perforation and for hearing improvement using pure tone audiometry. Results: Among 30 cases of PRP group, there were 29 cases of closure of perforation (96.67 %) and 1 case had no closure of perforation (3.33 %). Among 30 cases of T group, there were 28 cases of closure of perforation (93.33%) and 2 cases had no closure of perforation (6.67%). The p-value calculated between the groups with pre operative mean air bone gap values was 0.2210 and that with post operative values was 0.1835; indicating no signicant difference between the groups during follow up at 6 months.