Comparative Study of Recovery after Sevoflurane versus Halothane Anaesthesia in Adult Patients

Ravi, P. K.; Nanda, HS; Anant, S

doi:10.1016/s0377-1237(08)80011-1

Cited by 7 publications

(8 citation statements)

References 11 publications

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“…[ 20 ] It is again used in many studies for assessing postoperative cognitive recovery. [ 21 22 23 ] Our results were in agreement with those of Dashfield et al . [ 23 ] where there was no significant difference in the P-deletion scores between the two groups, that is, VCI with sevoflurane and IV induction with propofol.…”

Section: Discussionsupporting

confidence: 93%

Comparison of vital capacity induction with sevoflurane to intravenous induction with propofol in adult patients

2014

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Background:Various techniques exist for gaseous induction in adults. Vital capacity induction (VCI) is a special technique for gaseous induction of anesthesia.Aims:We compared the two methods for time of induction, vital parameters at induction, and suitability for laryngeal mask insertion and its effects, if any on the emergence and postoperative cognitive function tests.Settings and Design:A total of 60 adult American Society of Anesthesiologists grades I and II gynecological patients were randomly allocated into two groups of 30 each.Materials and Methods:Group “S” received VCI with 8% sevoflurane in 8 l/min oxygen and group “P” received intravenous induction with propofol after premedication. Laryngeal mask airway (LMA) was inserted and anesthesia maintained with oxygen, nitrous oxide, and sevoflurane in both groups. Induction time, corresponding entropy, vital parameters, and emergence time were noted. Postoperative cognitive and psychomotor functions were noted with P-deletion test, digit symbol substitution test, and finger nose test.Statistical Analysis Used:Unpaired t-test and Fisher exact test.Results:Time for induction was 61 ± 32 s and 31 ± 10.8 s for VCI (group S) and propofol (group P), respectively. The difference was statistically significant (P = 0.001). About 70% patients in VCI had excellent conditions for LMA insertion when compared with 76% in propofol group (P = 0.3855). The incidence of airway complications, emergence times, and recovery of postoperative cognitive functions was not significantly different in both groups.Conclusions:VCI provides an induction and recovery comparable to propofol induction.

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Section: Discussionsupporting

confidence: 93%

Comparison of vital capacity induction with sevoflurane to intravenous induction with propofol in adult patients

2014

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“…Another study has considered postoperative agitation as an abnormal and scary behavior (18). Postoperative agitation is commonly performing for preschool children after receiving inhalation anesthetic agents such as sevoflurane (19), desflurane (20), and isoflurane (21,22). In the present study, hemodynamic parameters were evaluated, and no difference in systolic pressure, diastolic pressure, and arterial oxygen saturation was observed, but heart rate was significantly decreased in the T group (P = 0.01).…”

Section: Discussionmentioning

confidence: 56%

A Comparison of the Sevoflurane and Total Intravenous Anesthesia on the Quality of Recovery in 2 to 10-Year-Old Children

et al. 2020

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Background: Inhalant anesthesia is one of the mainstays of pediatric anesthesia, and it is considered by the majority of pediatric anesthetists worldwide as the gold standard. On the other hand, total intravenous anesthesia (TIVA) is a very popular choice for routine pediatric anesthesia practice. Therefore, utilization of TIVA compared to the volatile anesthesia is still a topic of debate in successful anesthesia management. Objectives: To compare TIVA vs sevoflurane-based anesthesia on the quality of recovery in children aged 2 to 10 years who had outpatient surgery. Methods: Eighty children, aged 2 to 10 years old undergoing outpatient surgery, were randomly divided into two groups (40 patients each). The TIVA group with propofol (T) received general anesthesia induced with midazolam 0.03 - 0.05 mg/kg, fentanyl 1 mcg/kg, propofol 3 - 5 mg/kg, 0.1 mg/kg lidocaine and maintenance with propofol 100 to 250 μg/kg.min and remifantanil 0.1 mcg/kg. The sevoflurane (S) group received general anesthesia induced with midazolam 0.03 - 0.05 mg/kg, fentanyl 1 mcg/kg, O2/sevoflurane 8 vol%, maintenance with 2 - 3 vol%. Demographic characteristics, awakening quality in recovery, hemodynamic status, and other complications such as patient agitation, pain, nausea, and vomiting were evaluated in both groups. Results: Patients did not differ significantly in terms of demographic characteristics. The incidence of postoperative agitation was 62% higher in the sevoflurane group than the TIVA group (5%, P < 0.001). The highest percentage of pain was obtained as 52.5% in the sevoflurane group. Postoperative nausea and vomiting did not differ significantly among groups, and there was a significant decrease in the heart rate of the subjects in the T group as one of the hemodynamic variables (P = 0.01). Conclusions: Inhalation anesthesia with sevoflurane led to more rapid recovery from anesthesia, and TIVA with propofol injection reduced post-operative pain and agitation compared to patients receiving sevoflurane. Therefore, TIVA with propofol infusion is probably an effective technique to maintain general anesthesia in pediatric outpatient surgery and to increase parental satisfaction, and to reduce the workload of recovery room staff.

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“…Sevoflurane, an inhaled anesthetic often used in children, is associated with rapid induction and emergence; its blood solubility is low and there is no airway stimulation. However, sevoflurane has been associated with various complications, including agitation on emergence, [1,18,24] particularly after pediatric ophthalmic surgery (the eyes are covered postoperatively). One study found that 44% of pediatric patients who underwent strabismus surgery showed emergence agitation.…”

Section: Discussionmentioning

confidence: 99%

“…The rapid recovery from sevoflurane anesthesia reduces the risks of coughing and respiratory complications. [1] However, a high incidence of agitation on emergence from anesthesia (50%–80%) has been reported in children who receive sevoflurane. [2] Postoperative agitation not only causes pain and delays discharge from the recovery room, but also requires medical treatment.…”

Section: Introductionmentioning

confidence: 99%

Effect of esmolol and lidocaine on agitation in awake phase of anesthesia among children

Park

Kim

et al. 2019

Chinese Medical Journal

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Background: Sevoflurane is widely used to anesthetize children because of its rapid action with minimal irritation of the airways. However, there is a high risk of agitation after emergence from anesthesia. Strabismus surgery, in particular, can trigger agitation because patients have their eyes covered in the postoperative period. The aim of this study was to determine whether or not esmolol and lidocaine could decrease emergence agitation in children. Methods: Eighty-four patients aged 3 to 9 years undergoing strabismus surgery were randomly assigned to a control group (saline only), a group that received intravenous lidocaine 1.5 mg/kg, and a group that received intravenous esmolol 0.5 mg/kg and lidocaine 1.5 mg/kg. Agitation was measured using the objective pain score, Cole 5-point score, and Richmond Agitation Sedation Scale score at the end of surgery, on arrival in the recovery room, and 10 and 30 min after arrival. Results: The group that received the combination of esmolol and lidocaine showed lower OPS and RASS scores than the other two groups when patients awoke from anesthesia (OPS = 0 (0–4), RASS = –4 [(–5)–1]) and were transferred to the recovery room (OPS = 0 (0–8), RASS = –1 [(–5)–3]) ( P < 0.05). There was no significant difference in the severity of agitation among the three groups at other time points ( P > 0.05). Conclusions: When pediatric strabismus surgery is accompanied by sevoflurane anesthesia, an intravenous injection of esmolol and lidocaine could alleviate agitation until arrival in the recovery room. Trial registration: Clinical Research Information Service, No. KCT0002925; https://cris.nih.go.kr/cris/en/search/search_result_st01.jsp?seq=11532

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Comparative Study of Recovery after Sevoflurane versus Halothane Anaesthesia in Adult Patients

Cited by 7 publications

References 11 publications

Comparison of vital capacity induction with sevoflurane to intravenous induction with propofol in adult patients

Comparison of vital capacity induction with sevoflurane to intravenous induction with propofol in adult patients

A Comparison of the Sevoflurane and Total Intravenous Anesthesia on the Quality of Recovery in 2 to 10-Year-Old Children

Effect of esmolol and lidocaine on agitation in awake phase of anesthesia among children

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