Comparative Study of the Antimicrobial Effect of Three Irrigant Solutions (Chlorhexidine, Sodium Hypochlorite and Chlorhexidinated MUMS)

Abstract

Aim To compare the antimicrobial effect of 2% chlorhexidine, 2.5% sodium hypochlorite and MUMS containing 2% chlorhexidine. Materials and methods All of the above irrigants were examined on Enterococcus faecalis, Streptococcus mutans, Candida albicans, Lactobacillus casei and E.coli. A total of 0.5 CC of each solution and 0.5 CC of McFarland solution bacterium were added to each examination tube. After 15, 30 and 45 minutes, colony count was performed for each tube. The difference in the number of bacteria indicated the effect taken by disinfectant material. Results MUMS containing chlorhexidine showed the antimicrobial properties just like chlorhexidine's effect against E.coli, Streptococcus mutans, Candida albicans, Enterococcus faecalis and Lactobacillus casei in preventing these entire microorganisms to incubate. Sodium hypochlorite was not effective against Enterococcus faecalis and Candida albicans incubated in 15, 30 and 45 minutes and Enterococcus faecalis in 15 minutes. Conclusion MUMS has antimicrobial properties similar to chlorhexidine. Clinical significance As MUMS containing chlorhexidine can transfer chlorhexidine through its own surfactant around apical area and it can open the dentinal tubules by its own chelator for more penetration of chlorhexidine, it may be a choice for canal irrigation. How to cite this article Bidar M, Hooshiar S, Naderinasab M, Moazzami M, Orafaee H, Naghavi N, Jafarzadeh H. Comparative Study of the Antimicrobial Effect of Three Irrigant Solutions (Chlorhexidine, Sodium Hypochlorite and Chlorhexidinated MUMS). J Contemp Dent Pract 2012;13(4): 436-439.

The Comparison of Apical Leakage between Two Obturation Techniques (Cold Lateral Condensation and Obtura II) by Using Fluid Filtration Method

“…This is considered as the most common way for transmission of bacteria in the canal (8). More than half of the endodontic failures are due to inability in preventing this leakage (1).…”

Sodium hypochlorite and chlorhexidine digluconate in endodontics

“…The disinfection of the root canal system has the effect of irrigating solutions, which must present an antibacterial action, dissolve necrotic tissue residues, promote lubrication to facilitate instrumentation and have biocompatibility with adjacent tissues so as not to injure the periapical tissues. Sodium hypochlorite and chlorhexidine, despite their different concentrations, are considered irrigating solutions conducive to endodontic treatment (Bidar et al, 2012;Elakanti et al, 2015;Jeansonne & White, 1994;Rossi-Fedele et al, 2012;Walia et al, 2019) 3.1 SODIUM HYPOCHLORITE Sodium hypochlorite was first used in 1792 under the name Javele water, a mixture of sodium and potassium hypochlorite. Some industrialists adhered to the use of sodium hypochlorite in the hygiene of vegetables and legumes, removing all microorganisms and bacteria that could directly affect the health of those who ingested the food.…”

“…Chlorhexidine is known as a chemical antiseptic substance that currently stands out due to its advantage in relation to good biocompatibility and absence of relative toxicity, in addition to its broad spectrum of antifungal and bactericidal action acting against Gram-positive and Gram-negative bacteria (aerobic, facultative anaerobic, viruses and fungi) ( Arslan et al, 2015;Bidar et al, 2012;Ferraz et al, 2007). In endodontics, most professionals and specialists recommend using chlorhexidine as an intracanal medication, as it provides a broad reduction of microorganisms in the canal.…”

“…This substance can be found in two ways: liquid or gel; Both methods of use, has a concentration of 0.2% to 2%. Research indicates that chlorhexidine gel has higher efficacy and performance compared to sodium hypochlorite (Bidar et al, 2012;Ferraz et al, 2007;Joy Sinha et al, 2017;Walia et al, 2019).…”