Comparative study of tramadol versus NSAIDS as intravenous continuous infusion for managing postoperative pain

Rodriguez, María Josefa; Torre, Matthew; Perez-Iraola, P.; Fernandez-Cuervo, C.; Benítez, Pedro Pablo Ferro; Navarro, Arturo Anadón; Vidal, Julie

doi:10.1016/s0011-393x(05)80639-3

Cited by 28 publications

(11 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…4 Other studies addressing the analgesic effect of NSAIDs in gynecological procedures have failed to demonstrate a significant reduction in either postoperative pain or the need for additional opioids. [8][9][10][11][12][13][14][15][16][17][18] Our pilot study and previous reports do not, however, support the equipotency of tramadol and indomethacin which may represent a limitation of our study. Tramadol is an effective analgesic which causes less respiratory depression than morphine.…”

Section: Discussioncontrasting

confidence: 58%

Postoperative analgesia with tramadol and indomethacin for diagnostic curettage and early termination of pregnancy

Khazin¹,

Weitzman²,

Rozenzvit-Podles³

et al. 2011

International Journal of Obstetric Anesthesia

View full text Add to dashboard Cite

Section: Discussioncontrasting

confidence: 58%

Postoperative analgesia with tramadol and indomethacin for diagnostic curettage and early termination of pregnancy

Khazin¹,

Weitzman²,

Rozenzvit-Podles³

et al. 2011

International Journal of Obstetric Anesthesia

View full text Add to dashboard Cite

“…Tramadol was significantly better than the other three agents with regard to the number of boluses required per patient and the number of patients requiring supplementary analgesia. However, Rodriguez et al 24 used an initial bolus of 660 mg dipyrone compared with 2 g in our study. These observations confirm the importance of dose selection in obtaining optimum efficacy in the treatment of postoperative pain.…”

Section: Discussionmentioning

confidence: 87%

“…These findings are consistent with those reported by Torres et al 10 in a study of postoperative pain after abdominal surgery in which dipyrone administered via PCA pumps had the same analgesic efficacy than buprenorphine and morphine with less adverse effects. In contrast, Rodriguez et al 24 reported higher analgesic effects for tramadol in a comparative study of tramadol versus NSAIDs for managing postoperative pain. A total of 160 patients undergoing abdominal hysterectomy were randomized to receive tramadol, dipyrone, ketorolac, and lysine clonixinate, with 40 patients in each group.…”

Section: Discussionmentioning

confidence: 89%

“…19 Tramadol infusion, in addition to on-demand intravenous (IV) tramadol boluses, has been used and recommended for intravenous analgesia in patients recovering from major gynecological operations. [20][21][22][23][24] This study was designed to compare the analgesic efficacy and safety of dipyrone and tramadol during the early postoperative period in patients undergoing abdominal hysterectomy. Both drugs were administered using continuous infusion plus limited on-demand boluses over a 24-hour period.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Efficacy and safety of dipyrone versus tramadol in the management of pain after hysterectomy: A randomized, double-blind, multicenter study

Torres

Rodriguez²,

Montero³

et al. 2001

Regional Anesthesia and Pain Medicine

View full text Add to dashboard Cite

show abstract

“…groups. A significant incidence of nausea (30–35%) has been reported when tramadol is used for postoperative pain management (27,29).…”

Section: Discussionmentioning

confidence: 99%

Comparison of caudal vs intravenous tramadol administered either preoperatively or postoperatively for pain relief in boys

Güneş

Gündüz

Ünlügenç

et al. 2004

Pediatric Anesthesia

View full text Add to dashboard Cite

Summary Background : In this study we compared caudal with intravenous (i.v.) tramadol given pre‐ or postoperatively for pain relief in boys having hypospadias repair. Methods : The study was approved by the Ethics Committee and informed written consent was obtained from the parents of each patient. Patients (n = 134), aged 1–3 years, American Society of Anesthesiologists (ASA) physical status I, scheduled for hypospadias surgery were recruited. The patients were randomly allocated to one of the four groups: group I (n = 33), received 2 mg·kg−1 (0.5 ml·kg−1) of caudal tramadol after the surgical procedure was completed, group II (n = 33) received 2 mg·kg−1 (0.5 ml·kg−1) of caudal tramadol before incision, group III (n = 34) received 2 mg·kg−1 tramadol intravenously, after surgery and group IV (n = 34) received 2 mg·kg−1 tramadol intravenously, after anaesthesia induction. When the patients were fully awake in the recovery area, heart rate, arterial pressure, peripheral oxygen saturation, respiratory rate, pain and sedation scores were recorded at 5, 10, 15, 30, 60 min, and 2, 3, 4, 6, 12 and 24 h postoperatively and side‐effects were noted. Pain was assessed using an objective pain score (OPS). Results : The OPS were lower in caudal tramadol groups than in i.v. tramadol groups only at 3 h (P < 0.05). The duration of postoperative analgesia was longer in the caudal groups than in the i.v. groups (P = 0.001). However, the duration of postoperative analgesia was unaffected by the timing of administration. Conclusions : Caudal tramadol provides better and longer lasting postoperative analgesia than i.v. tramadol. These results also suggest that preoperative caudal tramadol did not provide any clinically perceptible benefits compared with postoperative caudal tramadol.

show abstract

Comparative study of tramadol versus NSAIDS as intravenous continuous infusion for managing postoperative pain

Cited by 28 publications

References 13 publications

Postoperative analgesia with tramadol and indomethacin for diagnostic curettage and early termination of pregnancy

Postoperative analgesia with tramadol and indomethacin for diagnostic curettage and early termination of pregnancy

Efficacy and safety of dipyrone versus tramadol in the management of pain after hysterectomy: A randomized, double-blind, multicenter study

Comparison of caudal vs intravenous tramadol administered either preoperatively or postoperatively for pain relief in boys

Contact Info

Product

Resources

About