Comparative study on histological changes around ulcer lesion and secretory function between peptic ulcer and ulcerative type of early cancer of the stomach

Electrophoretic Analysis of Acid Proteolytic Zymogens in Mucosa Surrounding Gastric Ulcer

“…Since atrophic changes of gastric mucosa are known to exist in the confined area around gastric ulcer as reported in the previous study (Ishimori et al 1974), the comparative study on histology and electrophoretic pattern of acid proteolytic zymogens of gastric mucosa with or without involvement of atrophic process was carried out in patients with gastric ulcer.…”

“…The scar observed in this study was identified unquestionably from the endoscopic point of view. However, since atrophic changes of gastric mucosa around ulcer are known to remain relatively unchanged after healing (Ishimori et al 1974), its clinical significance may be limited.…”

“…However, details still remain un known as to whether the distribution of acid proteolytic zymogens in gastric mucosa is related to any changes in certain clinical entities which involve histological 3hanges of gastric mucosa. The present study was designed to investigate this problem on gastric ulcer which is known to accompany atrophic changes in the mucosa surrounding ulcer lesion (Ishimori et al 1974). …”

Comparative Study on Gastric Secretory Function between Benign Gastric Polyp and Elevated Type of Early Stomach Cancer with Special Reference to Histological Findings of Gastric Mucosa

“…The cases of elevated type of early cancer of the stomach consisted of 7 cases of type I and 14 cases of type IIa according to the classification of Japanese Endoscopic Society. Multiple specimens were obtained from the mucosa of the anterior and the posterior wall according to the rule of Ishimori et al (1974) …”