Comparative study to evaluate the effect of colloid coloading versus crystalloid coloading for prevention of spinal anaesthesia induced hypotension and effect on fetal Apgar score in patients undergoing elective lower segment caesarean section: a prospective observational study

Abstract

Background: Spinal anesthesia for LSCS has a high incidence of maternal hypotension which can be severe and disastrous for the fetus and the mother. Coloading in these patients is a physiologically more appropriate method for preventing spinal anesthesia induced hypotension.Methods: 100 ASA I patients for elective LSCS were randomly divided into two equal groups to either receive 1000ml colloid (6% Hetastarch) or 1000ml crystalloids (Ringer lactate) as coload. NIBP, heart rate SPO2 and incidence of nausea and vomiting and use of ephedrine to treat any hypotension was recorded. Fetal outcome was measured using APGAR score at 0, 1 and 5 minutes.Results: The incidence of hypotension was lesser with colloid coload group (41.7%) as compared to the crystalloid coload group (58.3%) but the difference between the two groups was statistically insignificant. Similarly, no statistically significant difference was noted in the incidence of nausea and vomiting and Fetal APGAR score between the two groups.Conclusions: Both Colloid and Crystalloid coloading is effective in decreasing the incidence of spinal anesthesia induced hypotension during LSCS with lesser incidence of hypotension and nausea vomiting with colloid coloading.

Comparative Dose–Response Study on the Infusion of Norepinephrine Combined with Crystalloid Coload versus Colloid Coload for Preventing Hypotension During Spinal Anesthesia for Cesarean Delivery

“…The comparison of colloid coload versus crystalloid coload without prophylactic vasopressor infusion in obstetric patients has been described previously. 17,22 According to the current international consensus statement, it was recommended to use vasopressors prophylactically. 21 We believe that in clinical practice, it is more appropriate to use fluid coload combined with prophylactic vasopressor infusion to prevent SAIH during cesarean delivery.…”

Appraisal of the Effect of Norepinephrine Versus Phenylephrine on Blood Pressure and Heart Rate During Spinal Anaesthesia for a Caesarean Section; A Quasi-Experimental Study

“…Spinal anaesthesia has become the standard of choice in almost all patients undergoing caesarean section because of its low cost, easy induction, and excellent efficacy. 1 It eliminates the most prevalent hazards of general anaesthesia, such as aspiration, difficulties in intubation, and undesirable consequences of general anaesthetics on the foetus. More than 80% of caesarean sections are now performed under spinal anaesthesia.…”