1988
DOI: 10.1016/0277-5379(88)90338-0
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Comparative toxicity of cisplatin, carboplatin (CBDCA) and iproplatin (CHIP) in combination with cyclophosphamide in patients with advanced epithelial ovarian cancer

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Cited by 81 publications
(44 citation statements)
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“…All the 22 dihydroxido complexes under study were injected into 15 RP-HPLC and their log k'0 values, i.e. the capacity factor extrapolated to 0% of organic co-solvent, namely MeOH, were measured (Table 1).…”
Section: Determination Of Extrapolated Capacity Factors Log K'0mentioning
confidence: 99%
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“…All the 22 dihydroxido complexes under study were injected into 15 RP-HPLC and their log k'0 values, i.e. the capacity factor extrapolated to 0% of organic co-solvent, namely MeOH, were measured (Table 1).…”
Section: Determination Of Extrapolated Capacity Factors Log K'0mentioning
confidence: 99%
“…By plotting the scores for two PCs it is possible to graphically find similarities and differences between objects. Figure 2A shows that the two main PCs (PC1 and PC2) based on the QM descriptors split the whole series of compounds in the two groups (1-22 and 23-53) characterised by different kind of 15 axial ligands. This result confirms that the previolusly selected series of QM descriptors (Table S1) 25 are not suited to exhaustively model the chromatographic behaviour of the whole series of platinum complexes.…”
Section: Qsrr Analysismentioning
confidence: 99%
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