This was our first year of a new (risky) experience, assuming a totally online edition, new editorial procedures, organization, and layout. Happening in a year definitively marked by the extraordinary global crisis caused by this SARS COVID19 changing the definition of "normality" in all aspects of our life.Biomedical and Biopharmaceutical Research journal is no exception. The year of our full open access was simultaneously, the year of many other changes and impacts. Crisis always give space to opportunities, and we did got ours. BBR journal achieved to be more professional and available. Closer to the authors, to the reviewers and editors interacting in a regular way. Stronger in its processes and therefore more rigorous and transparent, in the right track for consolidation. This is no doubt, the most productive editorial year ever in the history of BBR. Our options were clearly accepted by our authors. We read these outcomes as a trust token that we deeply appreciate. Our success is their success. Therefore, we will continue to do more and better for this instrument of scientific culture specially conceived and reasoned in the common language of our Portuguese speaking communities.We stress our independent character, non-profit defined, exclusively based in the science and education, wholeheartedly dedicated to the growth of scientific culture. This is part of our foundation and our compromise for the future. This 2020 closure number includes two articles in the Nutrition and Food Sciences section, six articles in the Biomedical Sciences section and six others in the Biopharmaceutical Sciences section. Three other documents complete this number -the Proceedings Book of the 55th Annual Congress of the Brazilian Society of Physiology which included the 1st Portuguese-Brazilian Physiology Meeting organized by both countries' (sister) Physiology Societies, the Proceedings Book from the 2020 CBIOS Science Sessions, and the Proceedings Book from the IV CBIOS Seminar 2020.