“…The second updated searches of seven systematic reviews (extending from April 15, 2013 to April 26, 2019) for this guideline yielded 842 articles (after duplicates removed), of which 32 were relevant and 19 RCTs (reported in 21 articles) had a low risk of bias (Apeldoorn et al, 2017;Bjornsson Hallgren et al, 2017;Calvo-Lobo et al, 2018;Chary-Valckenaere et al, 2018;Devereaux et al, 2016;Goksu et al, 2016;Haik et al, 2017;Heron et al, 2017;Holmgren et al, 2012;Kibar et al, 2017;Kolk et al, 2013;Kromer et al, 2014;Kvalvaag et al, 2017Kvalvaag et al, , 2018Li et al, 2017;Littlewood et al, 2016;Mintken et al, 2016;Nazligul et al, 2018;Perez-Merino et al, 2016;Perez-Palomares et al, 2017;van der Dolder et al, 2015) and 11 studies had a high risk of bias (Beaudreuil et al, 2015;Del Castillo-Gonzalez et al, 2016;Ketola et al, 2017;Lugo et al, 2016;Moezy et al, 2014;Osteras & Torstensen, 2010;Pan et al, 2016;Rueda et al, 2016;Seven et al, 2017;Subasi et al, 2016;Zhang et al, 2016;Appendices VIB and VIII). Four of those 21 articles reported outcomes of different follow-ups based on two RCTs conducted by Kvalvaag et al (2017Kvalvaag et al ( , 2018 Kromer et al, 2014;…”