Comparing the photopic ERG i‐wave in different species

Rosolen, Serge G.; Rigaudière, Florence; Legargasson, J. F.; Chalier, C.; Rufiange, Marianne; Racine, Julie; Joly, Sandrine; Lachapelle, Pierre

doi:10.1111/j.1463-5224.2004.04022.x

Cited by 46 publications

(34 citation statements)

References 7 publications

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“…Kommonen et al [8] demonstrated that dogs anesthetized with a fast injection of propofol had an obvious increase in the amplitude of the bwaves. In recent years, ketamine, xylazine, and medetomidine have been used as anesthetic agents for conducting ERG examinations [4,12].…”

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confidence: 99%

The Effects of Different Anesthetic Agents on Short Electroretinography Protocol in Dogs

et al. 2009

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ABSTRACT. The purpose of this article was to investigate the effects of sedatives and general anesthetics, such as tiletamine-zolazepam, medetomidine, and isoflurane on the short ERG protocol. Six healthy mongrel dogs were assessed by a convenient short ERG protocol with the owners' consent. The amplitudes of a-wave and b-wave, as well as the implicit time of ERG under different anesthesia statuses, were recorded and analyzed. The amplitudes of ERG waves were not significantly different between tiletamine-zolazepam and medetomidine groups, except in b-wave after 5 min dark adaptation (140  42 V in tiletamine-zolazepam and 101  32 V in medetomidine, p<0.01). The amplitude of ERG recorded in isoflurane (5  3 V of a-wave and 12  6 V of b-wave under light adaptation; 41  19 V of b-wave after 1 min dark adaptation; 28  15 V of a-wave and 58  32 V of b-wave after 5 min dark adaptation) were significantly different from tiletamine-zolazepam (8  2 V of a-wave and 24  9 V of b-wave under light adaptation; 117  44 V of bwave after 1 min dark adaptation; 59  18 V of a-wave and 140  42 V of b-wave after 5 min dark adaptation), except in a-wave after 1 min dark adaptation (39  13 V in tiletamine-zolazepam and 34  17 V in isoflurane). Comment-General anesthesia had significantly lower amplitudes in the dark-adapted group compared with the sedation group. Therefore, tiletamine-zolazepam is a desirable choice for the short ERG protocol in dogs.

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confidence: 99%

The Effects of Different Anesthetic Agents on Short Electroretinography Protocol in Dogs

et al. 2009

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“…In the earlier studies [10,11,12,13], the PhNR analysis was made in the recordings of photopic ERG that was elicited by a short stimulus (<6 ms), and the amplitude of the PhNR might be affected by the i-wave [16,17,18]. The photopic ERG using long-duration (150 ms) stimuli can minimize the influence of the i-wave, which is thought to be associated with the off component [10, 18, 19] of the photopic ERG.…”

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confidence: 99%

Photopic Negative Response Reflects Severity of Ocular Circulatory Damage after Central Retinal Artery Occlusion

et al. 2009

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Purpose: To determine the relationship of the photopic negative response (PhNR) of the photopic electroretinogram (ERG) with the degree of circulatory disturbances in eyes following central retinal artery occlusion (CRAO). Methods: The circulatory disturbance was graded as mild (group 1) when the arm-to-retina transmission time was <30 s, moderate (group 2) when the time was >30 s and severe (group 3) when concurrent choroidal circulatory damage was found. For statistical analysis, groups 1, 2 and 3 were scored as 1, 2 and 3, respectively. Photopic ERGs were elicited by either short-flash (SF) or long-flash (LF) stimuli. Results: Both the SF and LF PhNR were significantly reduced in groups 2 and 3. The PhNR amplitude was negatively correlated with the severity of the ocular circulatory disturbances (p = 0.0498, ρ = –0.507 for SF PhNR; p = 0.0050, ρ = –0.750 for LF PhNR). Conclusion: The amplitude of the PhNR became more reduced as the severity of the circulatory disturbances increased in eyes with CRAO.

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“…ERG exams have been performed in the latest years with the use of xylazine, ketamine and medetomidine as anesthetic agents (Chaudieu 2004, Rosolen et al 2004). The combination of xylazine and butorphanol in this study, provided a good sedation and allowed adequate recording and low noise interference.…”

Section: Discussionmentioning

confidence: 99%

Normal values of b-wave responses of full-field electroretinogram in Lhasa Apso dogs with cataracts according to age

et al. 2015

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Lhasa Apso dogs with immature, mature or hypermature cataracts were divided into four groups according to their age (G1: 1 to 3 years old, G2: 4 to 7 years old, G3: 8 to 11 years old, G4: more than 12 years old). All animals were evaluated under the same sedation protocol to allow the performance of the electroretinogram (ERG) exam to determine normal value of b-wave response of the full-field ERG according to age. Three ERG responses were recorded: rod, maximal and cone responses. The amplitude values and b-wave implicit time of the responses of all groups were compared and analyzed by Kruskal-Wallis test (variance analysis for non-repeated measures), followed by the Dunn post-test (when p<0,05). A significant decrease was observed in maximal responses' amplitude, when comparing the G4 group with G1 and G2. No statistically relevant differences were observed in the b-wave implicit time values between groups. The ERG values are directly influenced by the animal's age. Older patients presented a decrease in the amplitude of the maximal response. The study determined the normal parameters of ERG b-waves for Lhasa Apso dogs with cataract according to their age group.

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Comparing the photopic ERG i‐wave in different species

Cited by 46 publications

References 7 publications

The Effects of Different Anesthetic Agents on Short Electroretinography Protocol in Dogs

The Effects of Different Anesthetic Agents on Short Electroretinography Protocol in Dogs

Photopic Negative Response Reflects Severity of Ocular Circulatory Damage after Central Retinal Artery Occlusion

Normal values of b-wave responses of full-field electroretinogram in Lhasa Apso dogs with cataracts according to age

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