Comparison between Blood Serum of Liver Cancer Patients and Healthy Controls Using UV–Visible Technology

Abstract

Background: It is fundamental to investigate the physical and chemical changes occurring in tissues and cells due to certain diseases. Objective: Early diagnosis of liver cancer through spectral analysis of serum samples of patients and healthy subjects. Patients and methods: Fifty-two samples from liver cancer patient, and 45 from healthy, using UV-visible spectroscopy technology. By using the statistical program (version 20) and independent samples t-test, the averages of the blood serum for males with new case liver cancer were the highest compared to that of control group. Results: Concerning the male patients with liver cancer who took chemotherapy and for all wavelengths except 225 nm, their blood serum average was higher compared to healthy subjects, and it was not statistically significant. Regarding the women who took chemotherapy, the situation of the absorption is seen to opposite to that the males who took chemotherapy too. Conclusion: The results showed that there are statistically significant differences between the spectrum of liver cancer patients and healthy people.