“…Two others randomly assigned use of each sampling device to certain time blocks (34, 45). The most popular and perhaps most economical design was the use of each subject as her own control, used in 14 studies (42%) (28–32, 35–37, 39–41, 52, 53, 55). This involved taking samples with both experimental and control devices from a subject in a single session or, as in two cases, comparison with smears taken from the same subjects the year before.…”