Comparison Between the Effects of Alfentanil, Fentanyl and Sufentanil on Hemodynamic Status During Rapid Sequence Intubation in the Emergency Department

Pouraghaei, Mahboub; Moharamzadeh, Payman; Soleimanpour, Hassan; Rahmani, Farzad; Safari, Saeid; Mahmoodpoor, Ata; Bakhtavar, Hanieh Ebrahimi; Esfanjani, Robab Mehdizadeh

doi:10.5812/aapm.14618

Cited by 31 publications

(34 citation statements)

References 19 publications

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“…There are several other trials of intubation with fentanyl or other similar opiates that compared it to no intervention or lidocaine; these studies found that opiates can attenuate the sympathomimetic response to intubation better than placebo or lidocaine (31)(32)(33)(34)(35). The only caveat to the use of fentanyl is to ensure an adequate dose is used.…”

Section: Resultsmentioning

confidence: 99%

Intubation of the Neurologically Injured Patient

Bucher

Koyfman

2015

The Journal of Emergency Medicine

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Section: Resultsmentioning

confidence: 99%

Intubation of the Neurologically Injured Patient

Bucher

Koyfman

2015

The Journal of Emergency Medicine

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“…Managing the respiratory status and level of tissue oxygenation is important in treating trauma patients in the emergency department and should be one of the first steps in patient evaluation. Urgent action should be taken to improve respiratory status, and taking care of the neck spine of trauma patients is essential before any diagnostic intervention (11, 12). …”

Section: Discussionmentioning

confidence: 99%

Effect of Neck Collar Fixation on Ventilation in Multiple Trauma Patients

Rahmani¹,

Pouraghaei²,

Moharamzadeh³

et al. 2016

Trauma Mon

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BackgroundAccording to the guidelines for treatment of multiple trauma patients, immobilization of the neck and neck collar fixation are essential. However, following neck collar fixation patients usually experience dyspnea. Some studies have found that neck collar fixation can lead to decreased pulmonary volumes, yet there have been no studies on the effect of neck collar fixation on patient ventilation.ObjectivesThe purpose of this study was to determine the effect of neck collar fixation on ventilation in multiple trauma patients.MethodsThis study was a descriptive-analytical study, which was performed in the emergency department of Tabriz University of Medical Sciences on multiple trauma patients with a Glasgow Coma Score (GCS) of 15. The effect of neck collar fixation on ventilation in the study participants was examined with the use of capnography.ResultsThis study involved 163 multiple trauma patients. Of these, 65% were male. The mean of end tidal carbon dioxide (ETCO2) of the patients without neck collars was 34.62 ± 4.46 and the mean ETCO2 of the patients with neck collars was 34.21 ± 2.31. There was no significant difference between the means of ETCO2, before and after removing the neck collar, among the studied patients (P = 0.196).ConclusionsAccording to the results of our study, neck collar fixation has no effect on ventilation in multiple trauma patients.

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“…Fentanyl and alfentanil minimize changes in heart rate and blood pressure during intubation of trauma patients. 73 In a prospective, randomized non-obstetric study of patients with baseline hypertension, fentanyl (with and without lidocaine) decreased but did not eliminate the hemodynamic response to laryngoscopy. 74 In a randomized trial of obstetric patients, fentanyl 1 lg/kg administered three minutes before induction of general anesthesia resulted in a stable hemodynamic profile during laryngoscopy, without affecting Apgar scores or blood gas analysis.…”

Section: Hemodynamic Considerationsmentioning

confidence: 99%