Phytoremediation technology incorporates living plants for in situ remediation of contaminated soils, sediments, tailings and groundwater. These practices integrates the removal, or degradation of toxic wastes that is capable of cleaning up an area with low to moderate levels of contamination. Phytoremediation has been studied widely for metals, pesticides, solvents, explosives, crude oil, etc. These studies and research are advanced, especially in small-scale operations. Phytoremediation has been successfully tested to decontamination of radioactive sites. The chapter initiates with possible remediation methods used for radioactive wastes where we will discuss types and nature of radioisotope contamination. Then we discuss discusses the classifications of phytoremediation techniques to treat radioactive contaminated waste. Phytoremediation performance depends on numerous factors such as soil composition, level of toxicity, suitable plant species, etc. Conversely, phytoremediation prospects low cost, practical and ecologically viable approach for low-level radiation waste clean-up.