Comparison of 3D conformal radiation therapy and intensity-modulated radiation therapy in patients with endometrial cancer: efficacy, safety and prognostic analysis

Abstract

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Radiation Therapy Techniques and Treatment-Related Toxicity in the PORTEC-3 Trial: Comparison of 3-Dimensional Conformal Radiation Therapy Versus Intensity-Modulated Radiation Therapy

“…Our study showed that IMRT resulted in fewer grade > 3 AE, mostly gastro-intestinal, during treatment, which is consistent with findings of similar studies on the effect of IMRT for cervical or endometrial cancer on treatment-related acute AE. [4,5,19] Besides fewer grade > 3 AE, others additionally reported fewer grade > 2 gastro-intestinal AE during and directly after IMRT, but this could not be confirmed in the present study. [5,9] We did observe significantly fewer grade > 2 AE during follow-up, mainly diarrhea and hematological AE, for women who received IMRT compared to 3DCRT, even up to 5 years, which is in line with other reports on the long-term effects of IMRT versus 3DCRT for women with gynecological malignancies.…”

WITHDRAWN: Radiation-induced acute injury of intensity-modulated radiotherapy versus three-dimensional conformal radiotherapy in induction chemotherapy followed by concurrent chemoradiotherapy for nasopharyngeal carcinoma: a prospective cohort study

“…IMRT and 3D-CRT have been demonstrated an improved treatment outcome and lower skin toxicity in other head and neck cancer, they are the primary radiotherapy techniques for cancer patients during recent decades [18]. However, the prevalence of radiation-related complication with induction chemoradiotherapy in the current literature varies widely [19][20][21]. There is still a lack of evidence and controversy comparing IMRT with 3D-CRT for NPC.…”

Comparison of the Efficacy of adjuvant External Beam Radiotherapy, Vaginal Brachytherapy, and External Beam Radiotherapy with Vaginal Brachytherapy in Patients with FIGO Stage IB Endometrioid carcinoma: A Meta-Analysis

“…Published literature indicates that the toxic reactions of EBRT mainly include pain, fatigue, hearing impairment, dermoreaction, genitourinary reactions (thamuria, urinary incontinence, cystitis), gastrointestinal reactions (nausea, diarrhea, intestinal obstruction, fecal incontinence), neurological complications (motor neuropathy, sensory neuropathy), soft tissue reactions, and pelvic insu ciency fractures [5,[10][11][12]. Research by Professor Ta M-H and colleagues [37] revealed that the most common toxic reactions are gastrointestinal and genitourinary reactions. Professor Stephanie M. de Boer reported that patients undergoing EBRT treatment experience more intestinal symptoms, which affect daily activities [26].Professor Nout RA found through HRQL analysis that patients receiving EBRT treatment are more likely to need to be close to the toilet due to intestinal issues, which severely restrict their daily activities [24].…”