Comparison of agreement of cervical spine degenerative pathology findings in magnetic resonance imaging studies

Fu, Michael C.; Webb, Matthew L.; Buerba, Rafael A.; Neway, William E.; Brown, James E.; Trivedi, Mitesh; Lischuk, Andrew; Haims, Andrew; Grauer, Jonathan N.

doi:10.1016/j.spinee.2015.08.026

Cited by 21 publications

(23 citation statements)

References 20 publications

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“…Signal variations of the discs on T2-weighted images (T2WIs) determinate the degrees of disc degeneration. [7,8] Among the MRI technologies, T2 ∗ mapping provides information on spatial macromolecule architecture and its interaction with water molecule mobility, can be used to detect early abnormalities in the lumbar IVD and endplate, and track response to therapy. [9–12] …”

Section: Introductionmentioning

confidence: 99%

Correlation between T2* (T2 star) relaxation time and cervical intervertebral disc degeneration

Huang

Guo

et al. 2016

Medicine

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Purpose:To demonstrate the potential benefits of T2∗ relaxation time of intervertebral discs (IVDs) regarding the detection and grading of degenerative disc disease using 3.0-T magnetic resonance imaging (MRI) in a clinical setting.Materials and Methods:Cervical sagittal T2-weighted, T2∗ relaxation MRI was performed at 3.0-T in 61 subjects, covering discs C2–3 to C6–7. All discs were morphologically assessed based on the Pfirrmann grade, and regions of interests (ROIs) were drawn over the T2∗ mapping. Receiver operating characteristic (ROC) analysis was performed among grades to determine the cut-off values.Results:Cervical intervertebral discs (IVDs) of patients were commonly determined to be at Pfirrmann grades III to V. The nucleus pulposus (NP) values did not differ significantly between sexes at the same anatomic level (P > 0.05). In the NP, the T2∗ values tended to decrease with increasing grade (P < 0.000), and a significant difference was found in the T2 values between grades I to V (P < 0.05). T2∗ values based on disc degeneration level classification were as follows: grade I (>30 milliseconds), grade II (24.55–29.99 milliseconds), grade III (21.65–24.54 milliseconds), grade IV (18.35–21.64 milliseconds), and grade V (<18.34 milliseconds).Conclusion:Our standardized method of region-specific quantitative T2∗ relaxation time evaluation seems capable of characterizing different degrees of disc degeneration quantitatively. The T2∗ values obtained in these cervical IVDs may serve as baseline values for future T2∗ measurements in both healthy and degenerated cervical discs.

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Section: Introductionmentioning

confidence: 99%

Correlation between T2* (T2 star) relaxation time and cervical intervertebral disc degeneration

Huang

Guo

et al. 2016

Medicine

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“…Early studies were based on X-ray; Boijson [4] has first measured the sagittal diameter of the cervical spinal canal on a cervical lateral radiograph. And Pavlov et al and Torg et al used the ratio of the sagittal diameter of the cervical canal divided by the corresponding diameter of the vertebral body to indicate the degree of cervical canal stenosis [5][6][7].…”

Section: Introductionmentioning

confidence: 99%

“…Into the 21th century, MRI began to gradually rise and gradually to be the most commonly used imaging method for the CCS. Magnetic Resonance Imaging(MRI) measures not only the width and length of the spinal canal but also depicts in detail the soft tissue, intervertebral disks, the spine cord and ligaments which cannot be reflected by X-ray or CT [7][8][9]. Therefore, many doctors began to evaluate CCS from the perspective of MRI.…”

Section: Introductionmentioning

confidence: 99%

A New grading system based on T2-weighted axial MRI for Cervical Canal Stenosis

Wang¹,

Zhao²,

Wei³

et al. 2020

Preprint

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Background: Cervical Canal Stenosis (CCS) is a common cervical disease that occurs during and after middle age. There are a variety of grading systems and Measurement methods based on X-ray, Computed Tomography(CT) for cervical canal stenosis. Although many authors measured and classified cervical canal stenosis on the basis of T2-weighted sagittal MRI after the appearance of magnetic resonance, the research on Cervical Canal Stenosis remains to be improved.Purposes: To explore a more detailed grading system on MRI for cervical canal stenosis and could be used to the clinical diagnosis and treatment.Patient and Methods: We retrospectively studied 200 patients with cervical spinal stenosis. Cervical canal stenosis was classified according to the T2-weighted axial MRI with the most serious compression into the following grades: grade 0,normal; grade 1, mild canal stenosis with obliteration of anterior or posterior of cerebrospinal fluid (CSF) space ; grade 2, moderate canal stenosis with obliteration of both sides of the CSF space but no significant changes in spinal morphology; Grade 3, severe canal stenosis with spinal cord deformity, 3A the oppression ratio of cervical spinal cord is under 50%, 3B the oppression ratio of cervical spinal cord is between 50% to 75%, 3C the angle of the protrusion less than 90°; Grade 4, serious canal stenosis with spinal cord deformity and the oppression ratio of cervical spinal cord is exceeding 75%, 4A the non-ossification protrusion, 4B the ossific protrusion. We collected the relevant clinical and imaging data of the patients and analyzed the relationship between them and our new grading system. Patients were followed up one year later.Results: Our new grading system was easy to learn and communication. The the ICC reliabilities between six readers was between 0.817-0.865. And the Effective sagittal spinal canal was significantly different along with our grades at each disc level. In terms of clinical data, our grading system is correlated with the patient's preoperative JOA score and had impact on the choice of surgical strategy.Conclusions: We suggest our new grading system can provided as a reliable assessment that can guide clinical treatment for Cervical Canal Stenosis.

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“…Early studies were based on X-ray; Boijson [5] has rst measured the sagittal diameter of the cervical spinal canal on a cervical lateral radiograph. And Pavlov et al and Torg et al used the ratio of the sagittal diameter of the cervical canal divided by the corresponding diameter of the vertebral body to indicate the degree of cervical canal stenosis [6][7][8].…”

mentioning

confidence: 99%

mentioning

confidence: 99%

A New grading system based on T2-weighted axial MRI for Cervical Canal stenosis

Wang

Zhao

Wei

et al. 2020

Preprint

View full text Add to dashboard Cite

Background: Cervical Canal Stenosis (CCS) is a common cervical disease that occurs during and after middle age. There are a variety of grading systems and Measurement methods based on X-ray, Computed Tomography(CT) for cervical canal stenosis. Although many authors measured and classified cervical canal stenosis on the basis of T2-weighted sagittal MRI after the appearance of magnetic resonance, the research on Cervical Canal Stenosis remains to be improved. To explore a more detailed grading system on MRI for cervical canal stenosis and could be used to the clinical diagnosis and treatment.Methods: We retrospectively studied 200 patients with cervical spinal stenosis. Cervical canal stenosis was classified according to the T2-weighted axial MRI with the most serious compression into the following grades: grade 0,normal; grade 1, mild canal stenosis with obliteration of anterior or posterior of cerebrospinal fluid (CSF) space ; grade 2, moderate canal stenosis with obliteration of both sides of the CSF space but no significant changes in spinal morphology; Grade 3, severe canal stenosis with spinal cord deformity, 3A the oppression ratio of cervical spinal cord is under 50%, 3B the angle of the protrusion less than 90°; Grade 4, serious canal stenosis with spinal cord deformity and the oppression ratio of cervical spinal cord is exceeding 50%, 4A the non-ossification protrusion, 4B the ossific protrusion. We collected the relevant clinical and imaging data of the patients and analyzed the relationship between them and our new grading system. Patients were followed up one year later.Results: Our new grading system was easy to learn and communication. The the ICC reliabilities between six readers was between 0.817-0.865. And the Effective sagittal spinal canal was significantly different along with our grades at each disc level. In terms of clinical data, our grading system is correlated with the patient's preoperative mJOA score and had impact on the choice of surgical strategy. Conclusions: We suggest our new grading system can provided as a reliable assessment that can guide clinical treatment for Cervical Canal Stenosis.

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Comparison of agreement of cervical spine degenerative pathology findings in magnetic resonance imaging studies

Cited by 21 publications

References 20 publications

Correlation between T2* (T2 star) relaxation time and cervical intervertebral disc degeneration

Correlation between T2* (T2 star) relaxation time and cervical intervertebral disc degeneration

A New grading system based on T2-weighted axial MRI for Cervical Canal Stenosis

A New grading system based on T2-weighted axial MRI for Cervical Canal stenosis

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