Comparison of angiocardiographic and thermal washout technics for left ventricular volume measurement

Bartle, Stuart H.; Sanmarco, Miguel E.

doi:10.1016/0002-9149(66)90036-1

Cited by 45 publications

(4 citation statements)

References 72 publications

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“…This is also suggested by the tendency for the ejection fraction to maintain a constant value characteristic of each of the inotropic states in the two postures, indicating that variations in ventricular filling and the consequent effects upon stroke volume are accompanied by matching adjustments in peripheral vascular impedence structure. Because the ejection fraction appears to have a characteristic value for any given inotropic state over a relatively broad range of ventricular-loading conditions, it has been suggested as an index of myocardial contractility (59)(60)(61)(62)(63)(64)(65). The slight reduction of ejection fraction in the control tilted posture observed in this study suggests the possibility of a physical limit to which the ventricular wall can shorten.…”

Section: During Isoproterenol Infusionmentioning

confidence: 71%

The effects of posture and isoproterenol on the velocity of left ventricular contraction in man

Paley¹,

McDonald²,

Blumenthal³

et al. 1971

J. Clin. Invest.

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A B S T R A C T A study was performed in five normal men in whom left ventricular volume was measured by thermodilution in the supine and 600 head-up postures. in the control state, and then during steady-state response to isoproterenol. The mean rate of circumferential shortening of the left ventricle was calculated for each of the postures in both inotropic states and was found to remain constant in the control state at 12.5 ±0.6 cm/sec in the supine posture and 13.3 +0.5 cm/sec in the tilted posture. Similarly, mean rate of circumferential shortening remained constant in response to the positive inotropic effect of isoproterenol at 20.9 ±0.5 cm/sec in the supine position and 20.7 ±0.5 cm/sec in the tilted pos-

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Section: During Isoproterenol Infusionmentioning

confidence: 71%

The effects of posture and isoproterenol on the velocity of left ventricular contraction in man

Paley¹,

McDonald²,

Blumenthal³

et al. 1971

J. Clin. Invest.

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“…The technical errors with fast heart rates in small animals are formidable. Bartle and Sanmarco (1966) compared biplane angiocardiography with simultaneous thermodilution measurements in both men and dogs, and also found significantly larger values by thermodilution.…”

Section: Resultsmentioning

confidence: 99%

“…left ventricle of dogs showed equilibration of temperature by the second beat after injection in 75 per cent of cases. Swan and Beck (1960), however, have shown by cine-angiocardiography in animals that atrial blood appears in the ventricular outflow tract at the onset of systole, and Bartle and Sanmarco (1966) found that this also applied in man. While there is little doubt that left ventricular mixing is not always complete, indirect evidence that mixing is adequate is provided by Folse and Braunwald (1962), who used a praecordial counting technique after the injection of radio-active 1311 albumin.…”

Section: Resultsmentioning

confidence: 99%

Left ventricular volume in aortic stenosis measured by an angiocardiographic and a thermodilution method.

Fleming¹,

Hamer²

1968

Heart

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The action of the left ventricle is impaired in aortic stenosis to a variable degree, and since the extent of myocardial damage will influence the management and prognosis in the individual patient, some way of determining myocardial function is required. For a full assessment of left ventricular performance it is necessary to measure the changes in both volume and pressure throughout the cardiac cycle. Pressure measurements are easily obtained by left heart catheterization, but provide an incomplete picture if the left ventricular volume is not known. The heart size on the chest radiograph is often used in the estimation of left ventricular volume in aortic stenosis, but a more precise measurement is desirable. The two presently available methods of volume determination involve measurement of the angiocardiogram taken in two planes, or the injection of cold saline into the left ventricle and the recording of the beat by beat temperature change in the ascending aorta. These methods are subject to different technical difficulties, and, as neither has received wide acceptance as providing an accurate estimate of left ventricular volume, we have included both in our routine preoperative assessment of patients with aortic stenosis. In this report we give the results of volume measurements in aortic stenosis, compare the angiocardiographic with the thermodilution technique, and show the poor relation between these measurements and the size of the heart in the conventional radiograph. PATIENTS AND METHODSLeft ventricular volume measurements were made during the course of pre-operative left heart catheterizaReceived October 12, 1967. tion in 23 patients with aortic stenosis, aged from 9 to 62 years, the obstruction being at valve level in all but one, where the stenosis was a subvalvar fibrous ring (Table I). All patients were in sinus rhythm and, despite the frequent finding of an early diastolic murmur, none of the patients was judged on clinical or haemodynamic grounds to have significant aortic regurgitation. Volume measurements were not made when there was any mitral valve regurgitation.A postero-anterior chest radiograph was available, taken at a tube to film distance of six feet for each patient, and from this the heart size was expressed as the cardiothoracic ratio.In early studies promethazine (phenergan) 50 mg. was given intramuscularly before the procedure, but later investigations were carried out without premedication. Catheterization of the right heart from the right long saphenous vein using local skin anaesthesia was followed in each case by transseptal puncture, placing a Brockenbrough catheter in the left ventricle. A No. 6 Gensini catheter was placed in the femoral artery by the percutaneous method and advanced to the ascending aorta. The cardiac output was measured by the injection of indocyanine green into the left ventricle and the withdrawal of blood from the aorta through a Gilford cuvette, calibration being carried out by the dynamic method (Emanuel et al., 1966; Shineboume, Fleming, and Hamer...

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“…Angiocardiographic techniques to determine EDV and ESV are difficult and only a few measurements are possible because of the toxicity and the accumulation of the contrast material (Bartle & Sanmarco, 1966;Rapaport, 1966). Another frequently used technique is the indicator-dilution method (Holt, 1956;Thorpe FIG.…”

Section: (4) Stroke Volume End-diastolic and End-systolic Volumementioning

confidence: 99%

Some techniques used in clinical investigation of cardiovascular function in the dog

Delaunois

Rick

Mattheeuws

1976

J of Small Animal Practice

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Comparison of angiocardiographic and thermal washout technics for left ventricular volume measurement

Cited by 45 publications

References 72 publications

The effects of posture and isoproterenol on the velocity of left ventricular contraction in man

The effects of posture and isoproterenol on the velocity of left ventricular contraction in man

Left ventricular volume in aortic stenosis measured by an angiocardiographic and a thermodilution method.

Some techniques used in clinical investigation of cardiovascular function in the dog

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