Comparison of Anorectal Function Measured using Wearable Digital Manometry and a High Resolution Manometry System

Attari, Ali; Chey, William D.; Baker, Jason; Ashton‐Miller, James A.

doi:10.1101/2020.01.24.917922

Cited by 4 publications

(3 citation statements)

References 26 publications

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“…As this probe did not comply with the anorectal angle, greater force might be encountered due to the higher tissue contact stress (force per unit area), where the body of the probe is forced against the anorectal angle as well as the sphincters, rather than just measuring fluid pressure within the anus or rectum [14]. This hypothesis may be supported by the results of the study by Attari et al [21], who compared HRM to wearable pressure sensors mounted on a glove (digital manometry, DM) and found that the HRM catheter recorded higher pressures than the DM sensors. A possible explanation for lower pressures recorded by DM is that the finger can adapt to the anorectal angle and potentially avoid the tissue stress encountered by the stiffer standard probe.…”

Section: Discussionmentioning

confidence: 93%

Comparison of Anorectal Function as Measured with High-Resolution and High-Definition Anorectal Manometry

Banasiuk¹,

Dobrowolska²,

Skowrońska³

et al. 2021

Dig Dis

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Introduction: Anorectal manometry (ARM) provides comprehensive assessment of pressure activity in the rectum and anal canal. Absolute pressure values might depend on the catheter used. Objective: Our aim was to compare the results obtained by different anorectal catheters in children with functional anorectal disorders. Methods: Children diagnosed with functional defecation disorders based on the Rome IV criteria were prospectively enrolled. ARM was performed in the supine position successively using 2 different probes in each patient in random order. Resting, squeeze pressures, and bear-down maneuver variables obtained by high-resolution (2-dimensional [2D]) and high-definition (3-dimensional [3D]) catheters were compared. Results: We prospectively included 100 children {mean age 7.5 [standard deviation (SD) ± 4.3] years; 62 boys}. Mean resting pressures were significantly higher when measured with the 3D than with the 2D catheter (71 [SD ± 19.4] vs. 65 [SD ± 20.1] mm Hg, respectively; p = 0.000). Intrarectal pressure measured by 3D and 2D catheters was similar (35 vs. 39 mm Hg, respectively; p = 0.761), but the percent of anal relaxation appeared to be higher for the 3D than for the 2D probe (12 vs. 5%, respectively; p = 0.002). Dyssynergic defecation (DD) was diagnosed in 41/71 patients (57.7%) using the 3D probe and in 51/71 children (71.8%) using the 2D probe (p = 0.044). Cohen’s kappa showed only fair agreement between the catheters (κ = 0.40) in diagnosis of DD. Conclusions: Our study demonstrated significantly different values of pressures obtained with different types of catheters. Normal ranges for conventional manometry cannot be applied to high-resolution systems, and results obtained by different types of manometry cannot be compared without adjustments (NCT02812823).

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Section: Discussionmentioning

confidence: 93%

Comparison of Anorectal Function as Measured with High-Resolution and High-Definition Anorectal Manometry

Banasiuk¹,

Dobrowolska²,

Skowrońska³

et al. 2021

Dig Dis

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“…Previous studies have shown that the intrarectal pressure measured using high-resolution manometry is 80 mm Hg during simulated defecation and up to 200 mm Hg during squeezing. 20,21 In addition, the peak intrarectal pressure is higher in males than in females, which might contribute to male sex being a reported risk factor for AL. much higher than the anastomotic bursting pressure in our porcine model, the anastomotic bursting pressure in patients who undergo low anterior resection reportedly becomes much higher at 3-6 months after surgery.…”

Section: Discussionmentioning

confidence: 99%

Clinical impact of the triple‐layered circular stapler for reducing the anastomotic leakage in rectal cancer surgery: Porcine model and multicenter retrospective cohort analysis

Nakanishi

Fujimoto

Shimada

et al. 2021

Annals of Gastroent Surgery

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“…The HR-ARM catheter con guration consists of ve pressure sensors in the anal canal spaced 10 mm apart, two sensors on the distal end used to measure rectum pressure and balloon in ation, and one external reference sensor outside the body to assess atmospheric pressure. 9 The internal anal sphincter is a circular, smooth muscle innervated via the sacral nerves responsible for ensuring the anal canal closure at rest. 10 During the rst stage of the evacuation of feces, migrating contractions propel the colonic contents into the rectum.…”

Section: Introductionmentioning

confidence: 99%

Characterizing the Recto-Anal Inhibitory Reflex Parameters in Spinal Cord Injured Subjects Compared to Published Healthy Control Values

Rodriguez

Armstrong²,

Baker³

et al. 2023

Preprint

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Study Design: Cohort study design Objectives: (i) Compare Rectoanal Inhibitory Reflex (RAIR) parameters in spinal cord injury (SCI) patients vs. published healthy control (HC) values (ii) Explore correlations and associations between RAIR parameters and SCI duration, location, and AIS levels. Setting: University of Michigan Methods: Prospective analysis of SCI participants who underwent High Resolution-Anorectal Manometry (HR-ARM). RAIR was tested by inflating 50 ml into the rectal balloon and immediately deflating. RAIR presence = ≥25% of internal anal sphincter pressure [IAS] (mmHg) amplitude reduction. RAIR parameters included: IAS (mmHg), reflex duration [RD] (seconds), and amplitude reduction [AR] (%). Subjects were categorized by AIS level and completeness of injury. Results: 30 SCI (cervical= 20; thoracic= 10) subjects underwent HR-ARM. Demographics included: 80.0% male, 90.0% Caucasian, mean age of 48.3 (14.2) (Range:24-75), and mean BMI of 26.6 (7.0) (Range:16.9–41.2). SCI subjects have significant mean differences, RD (p=<0.001), and AR (p=<0.001), compared to HC (N = 21), but no significant mean differences in IAS pressure. There were no significant correlations between SCI injury duration and IAS (r=-.17; p=NS), RD (r=0.31; p=NS) and AR (r=-0.09; p=NS). No significant mean differences between SCI level and the AIS completeness within RAIR parameters. Conclusion: Cervical and Thoracic SCI subjects have abnormal RAIR parameters compared to healthy controls. As there is minimal scientific evidence demonstrating digital rectal stimulation [DRS] as an effective method of promoting IAS relaxation for stool evacuation, an altered RAIR response on HR-ARM for SCI subjects provides a scientific basis to determine the use of DRS for bowel evacuation.

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Comparison of Anorectal Function Measured using Wearable Digital Manometry and a High Resolution Manometry System

Cited by 4 publications

References 26 publications

Comparison of Anorectal Function as Measured with High-Resolution and High-Definition Anorectal Manometry

Comparison of Anorectal Function as Measured with High-Resolution and High-Definition Anorectal Manometry

Clinical impact of the triple‐layered circular stapler for reducing the anastomotic leakage in rectal cancer surgery: Porcine model and multicenter retrospective cohort analysis

Characterizing the Recto-Anal Inhibitory Reflex Parameters in Spinal Cord Injured Subjects Compared to Published Healthy Control Values

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